Biotin anti-mouse CD185 (CXCR5) Antibody
- 产品名称：
- Biotin anti-mouse CD185 (CXCR5) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 145509
- 产品应用：
- 145509
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- mCXCR5-transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone L138D7 staining works optimally at room temperature or 4°C. Unlike other chemokine receptor antibodies, avoid using L138D7 at 37°C.
- Product Citations
-
- Koh CH, et al. 2020. Cancer Immunol Res. 8:698. PubMed
- Waide ML, et al. 2020. Cell Rep. 33:108503. PubMed
- Kim Y, et al. 2015. PLoS One. 10:120294. PubMed
- LaFleur MW, et al. 2019. Nat Immunol. 20:1335. PubMed
- Chen JS, et al. 2022. Sci Immunol. 7:eabl5652. PubMed
- Biram A, et al. 2020. Cell Rep. 30:1910. PubMed
- Kato Y, et al. 2020. Immunity. 53(3):548-563. PubMed
- Yang K, et al. 2018. J Virol. 92:e00428. PubMed
- Biram A, et al. 2020. Bio Protoc. e3562:10. PubMed
- Yang BH, et al. 2020. Cell Reports. 27(12):3629-3645.e6.. PubMed
- Zeitr?g J, et al. 2021. Eur J Immunol. 51:408. PubMed
- Mandal RK, et al. 2021. Cell Reports. 35(6):109094. PubMed
- Reimer D, et al. 2020. Cell Reports. 32(6):108030. PubMed
- Haniuda K, et al. 2020. Cell Rep. 33:108333. PubMed
- Simoni L, et al. 2020. Cell Rep. 33:108330. PubMed
- Alterauge D, et al. 2020. Cell Rep. 33:108232. PubMed
- Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
- Du Z, et al. 2020. J Allergy Clin Immunol. . PubMed
- RRID
- AB_2562125 (BioLegend Cat. No. 145509) AB_2562126 (BioLegend Cat. No. 145510)
- Structure
- 42 kD, seven transmembrane protein
- Distribution
-
B cells and a subset of T cells in mouse spleen, Tfh cells, also expressed in lymph node, bone marrow, and brain
- Function
- B cell migration into follicles, possible regulatory role in B cell differentiation and Burkitt's lymphoma
- Ligand/Receptor
- BLC/CXCL13
- Cell Type
- B cells, T cells, Tfh
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Kaiser E, et al. 1993. Eur. J. Immunol. 23:2532.
2. Forster R, et al. 1994. Cell. Mol. Biol. 40:381.
3. Forster R, et al. 1994. Blood 84:830.
4. Forster R, et al. 1996. Cell 87:1037.
5. Wolf I, et al. 1998. J. Biol. Chem. 273:28831.
- Gene ID
- 12145 View all products for this Gene ID
- UniProt
- View information about CD185 on UniProt.org
