APC anti-mouse CD185 (CXCR5) Antibody
- 产品名称：
- APC anti-mouse CD185 (CXCR5) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 145505
- 产品应用：
- 145505
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- mCXCR5-transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Clone L138D7 staining works optimally at room temperature or 4°C. Unlike other chemokine receptor antibodies, avoid using L138D7 at 37°C.
- Product Citations
-
- Gogoi H, et al. 2020. Front Immunol. 1.620833333. PubMed
- Zhao J, et al. 2021. Emerg Microbes Infect. 10:913. PubMed
- Vanderleyden I, et al. 2020. Cell Rep. 30:611. PubMed
- Webb LMC, et al. 2021. Aging Cell. 20:e13295. PubMed
- Essig K et al. 2017. Immunity. 47(6):1067-1082 . PubMed
- Hayatsu N et al. 2017. Immunity. 47(2):268-283 . PubMed
- Jing L, et al. 2022. Front Immunol. 13:864995. PubMed
- Wang Z, et al. 2021. J Virol. 95:e0141421. PubMed
- Zhang X, et al. 2021. Front Immunol. 12:680068. PubMed
- Myers DR et al. 2019. Cell reports. 27(6):1858-1874 . PubMed
- Liao T, et al. 2017. Front Immunol. 8:1334. PubMed
- Volberding PJ, et al. 2021. Cell Reports. 35(8):109160. PubMed
- Zhang YN, et al. 2020. EBioMedicine. 56:102819. PubMed
- Martínez‐López M et al. 2019. Immunity. 50(2):446-461 . PubMed
- Yan J, et al. 2020. Cell Rep. 107820:31. PubMed
- Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
- Chen C, et al. 2021. J Virol. 95:e0082921. PubMed
- He C, et al. 2022. Nat Commun. 13:5459. PubMed
- Miyauchi K, et al. 2016. Nat Immunol. 17:1447-1458. PubMed
- Miyauchi K, et al. 2021. Nat Commun. 12:3789. PubMed
- Huang WC, et al. 2020. Adv Mater. 32:e2005637. PubMed
- Wan X, Thomas J, Unanue E 2016. J Exp Med. 213: 967 - 978. PubMed
- Timilshina M, et al. 2020. Cell Reports. 27(10):2948-2961.e7.. PubMed
- Li X, et al. 2021. Front Immunol. 12:779560. PubMed
- RRID
- AB_2561969 (BioLegend Cat. No. 145505) AB_2561970 (BioLegend Cat. No. 145506)
- Structure
- 42 kD, seven transmembrane protein
- Distribution
-
B cells and a subset of T cells in mouse spleen, Tfh cells, also expressed in lymph node, bone marrow, and brain
- Function
- B cell migration into follicles, possible regulatory role in B cell differentiation and Burkitt's lymphoma
- Ligand/Receptor
- BLC/CXCL13
- Cell Type
- B cells, T cells, Tfh
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Kaiser E, et al. 1993. Eur. J. Immunol. 23:2532.
2. Forster R, et al. 1994. Cell. Mol. Biol. 40:381.
3. Forster R, et al. 1994. Blood 84:830.
4. Forster R, et al. 1996. Cell 87:1037.
5. Wolf I, et al. 1998. J. Biol. Chem. 273:28831.
- Gene ID
- 12145 View all products for this Gene ID
- UniProt
- View information about CD185 on UniProt.org
