Purified anti-SCF Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 124	1

规格

价格

库存

100µg

￥ 124

Product Details

Verified Reactivity: Human, Mouse
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Recombinant human SCF
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 - 2.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2564302 (BioLegend Cat. No. 662502)

Structure: Homodimer (non-covalently linked).
Distribution: Cytoplasm and cytoskeleton.
Function: Stem Cell Factor (SCF) plays a role in the regulation of cell proliferation, melanocyte differentiation, innate immune response, hematopoiesis, stem cell maintenance, mast cell development, migration, and function. Binding of SCF to c-Kit leads to the activation of PI3 kinase, Src kinase, and several signaling pathways including JAK/STAT pathway (activation of STATs) and Ras/Erk pathway (transmit signals through adaptor protein Grb2).
Interaction: Mast cells, natural killer cells, dendritic cells, eosinophils, epithelial cells, endothelial cells, melanocytes, germ cells, cholangiocytes, platelets, myeloid leukaemia cells, and intestinal cells of Cajal.
Ligand/Receptor: c-kit (CD117)
Biology Area: Angiogenesis, Cell Biology, Immunology, Signal Transduction, Stem Cells
Molecular Family: Cytokines/Chemokines, Growth Factors
Antigen References: 1. Lu HS, et al. 1996. J. Biol. Chem. 271:11309.
2. Heissig B, et al. 2002. Cell 109:625.
3. Ronnstrand L. 2004. Cell Mol. Life Sci. 61:19-20.
4. Jin DK, et al. 2006. Nat. Med. 12:557.
5. Krishnamoorthy N, et al. 2008. Nat. Med. 14:565.
6. Ray P, et al. 2010. Ann. N. Y. Acad. Sci. 1183:104.
Gene ID: 4254 View all products for this Gene ID
UniProt: View information about SCF on UniProt.org