Purified anti-human CD199 (CCR9) Antibody
- 产品名称：
- Purified anti-human CD199 (CCR9) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 358902
- 产品应用：
- 358902
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Cells transfected with human CCR9
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- Povoleri GAM, et al. 2018. Nat Immunol. 1.765972222. PubMed
- Chng MHY, et al. 2020. Immunity. 51(6):1119-1135.e5.. PubMed
- Afzali B, et al. 2017. Nat Immunol. 18:813. PubMed
- RRID
- AB_2562298 (BioLegend Cat. No. 358902)
- Structure
- A member of G-protein coupled receptors which contains seven transmembrane domains. Human CCR9 has above 80% amino acid sequence homology with its mouse counterpart.
- Distribution
-
CD4+CD8+ thymocytes, γ/δ T cells, subset of memory T cells
- Function
- May direct the trafficking of developing T cells in the thymus and generation of gut-specific immunological memory; co-receptor for HIV-1
- Ligand/Receptor
- CCL25
- Cell Type
- T cells, Thymocytes
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Zaballos A, et al. 1999. J. Immunol. 162:5671.
2. Wurbel MA, et al. 2007. J. Immunol. 178:7598.
3. Wurbel MA, et al. 2006. Eur. J. Immunol. 36:73.
- Gene ID
- 10803 View all products for this Gene ID
- UniProt
- View information about CD199 on UniProt.org
