APC/Cyanine7 anti-human CD185 (CXCR5) Antibody
- 产品名称：
- APC/Cyanine7 anti-human CD185 (CXCR5) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 356925
- 产品应用：
- 356925
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human CXCR5-transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Additional Product Notes
- BioLegend is in the process of converting the name APC/Cy7 to APC/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our APC/Cyanine7 products. Please contact Technical Service if you have any questions.
- Product Citations
-
- Lion J, et al. 2018. Front Immunol. 8:1761. PubMed
- Frasca D, et al. 2018. PLoS One. 13:e0197472. PubMed
- Vanoni G, et al. 2021. eLife. 10:00. PubMed
- Li G, et al. 2021. Mol Ther Oncolytics. 22:507. PubMed
- RRID
- AB_2562592 (BioLegend Cat. No. 356925) AB_2562593 (BioLegend Cat. No. 356926)
- Structure
- G-protein coupled receptor, 7 transmembrane regions, 42 kD
- Distribution
-
Mature B cells, Follicular helper T cells, and Burkitt's lymphoma cells.
- Function
- Mediates cell migration to the B cell follicles in the secondary lymphoid organs
- Ligand/Receptor
- CXCL13
- Cell Type
- B cells, Tfh
- Biology Area
- Cell Biology, Immunology, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Ma CS, et al. 2012. J. Exp. Med. 209:1241.
2. León B, et al. 2012. Nat. Immunol. 13:681.
3. Crotty S. 2011. Annu. Rev. Immunol. 29:621.
4. Kerfoot SM, et al. 2011. Immunity 34:947.
5. Sáez de Guinoa J, et al. 2011. Blood 118:1560.
- Gene ID
- 643 View all products for this Gene ID
- UniProt
- View information about CD185 on UniProt.org
