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Purified anti-human CXCL5 (ENA-78) Antibody
产品名称:
Purified anti-human CXCL5 (ENA-78) Antibody
产品类别:
抗体
产品编号:
526201
产品应用:
526201
[价格]
规格 价格 库存
50µg ¥ 147 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant Mouse CXCL5
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

ELISA Capture - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by ELISA assay. A concentration of 1.5 ?g/ml of the capture antibody was utilized to generate the example standard curve. It is recommended that the end-user titrate each lot of reagents for optimal performance.

Application Notes

ELISA Capture:?To measure human CXCL5, this antibody can be used as a capture antibody in sandwich ELISA format and paired with the biotinylated J1119D2 antibody (Cat. No. 526304) as the detection antibody. Recombinant Human CXCL5 (ELISA Std.) (Cat. No.?573409) can be used as the protein standard.
Note:?For measuring?human CXCL5 in serum, plasma or cell culture supernatant,?LEGEND MAX? Human CXCL5 ELISA Kit with Pre-coated Plates (Cat. No.?440907?&?440908) is specially developed and recommended.

RRID
AB_2563676 (BioLegend Cat. No. 526201) AB_2563677 (BioLegend Cat. No. 526202)

Antigen Details

Structure
Chemokine
Distribution
Endothelial cells, fibroblasts, neutrophils, monocytes, macrophages, platelets, alveolar type II cells
Function
CXCL5 chemoattracts and activates neutrophils during inflammation, and it is induced by LPS and inflammatory cytokines. NH2-terminal truncation enhances, whereas citrullination decreases the chemotactic properties of CXCL5.
Interaction
Neutrophils
Ligand/Receptor
CXCR2
Cell Type
Endothelial cells, Fibroblasts, Neutrophils, Monocytes, Macrophages, Platelets, Eosinophils
Biology Area
Immunology, Innate Immunity
Molecular Family
Cytokines/Chemokines
Antigen References

1. Walz A, et al. 1991. J. Exp. Med. 174:1355.
2. Wuyts A, et al. 1999. J. Immunol. 163:6155.
3. Jeyaseelan S, et al. 2005. Am. J. Respir. Cell. Mol. Biol. 32:531.
4. Mei J, et al. 2010. Immunity 33:106.
5. Mortier A, et al. 2010. J. Biol. Chem. 285:29750.
6. Grommes J and Soehnlein O. 2011. Mol. Med. 17:293.
7. Liu Y, et al. 2011. J. Immunol. 186:3197.
8. Kuo PL, et al. 2011. J. Cell. Physiol. 226:1224.
9. Power CA, et al. 1994. Gene. 151:333.
10. Corbett MS, et al. 1994. Biochem. Biophys. Res. Commun. 205:612.

Gene ID
6374 View all products for this Gene ID
UniProt
View information about CXCL5 on UniProt.org

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