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Purified anti-mouse/human Galectin-3 (Mac-2) Antib
产品名称:
Purified anti-mouse/human Galectin-3 (Mac-2) Antib
产品类别:
抗体
产品编号:
126701
产品应用:
126701
[价格]
规格 价格 库存
50µg ¥ 71 1

产品详情

Product Details

Verified Reactivity
Mouse, Human
Reported Reactivity
African Green, Baboon, Cynomolgus
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human Recombinant (partial), amino acids 151-251
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
ICC - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 ?g per ml.?For immunocytochemistry, a concentration of < 0.5 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Based on immunogen information, clone Gal397 may recognize African Green Baboon and Cynomolgus. It is recommended to test the reagent for optimal performance for other species. Due to in-house testing, the purified format is not recommended for flow cytometry and intracellular flow cytometry.

Product Citations
  1. Palau V, et al. 2021. Int J Mol Sci. 23:. PubMed
  2. Palau V, et al. 2021. Int J Mol Sci. 22:. PubMed
  3. Joeh E, et al. 2021. Curr Protoc. 1:e104. PubMed
  4. Feng T, et al. 2020. EMBO Rep. 21:e50219. PubMed
  5. Du H, et al. 2021. Life Sci Alliance. 4: . PubMed
RRID
AB_1134255 (BioLegend Cat. No. 126701) AB_1134256 (BioLegend Cat. No. 126702)

Antigen Details

Structure
Human Galetcin-3 has 250 amino acids with a predicted molecular weight of 26 kD.
Mouse Galetcin-3 has 264 amino acids with a predicted molecular weight of 27.5 kD.
Distribution

Localized in the nucleus, cytoplasm, cell surface, or extracellular matrix. Expressed by tumor cells, monocytes/macrophages, epithelial cells, Kupffer cells, dendritic cells

Function
Regulate cell proliferation and differentiation, adhesion, anti-apoptosis
Ligand/Receptor
Variety ligands, such as IgE, IgA, galactose, casein kinase I, laminin, mucin, LAMPs, CD66, etc
Cell Type
Dendritic cells, Epithelial cells, Macrophages, Monocytes
Biology Area
Cell Adhesion, Cell Biology, Cell Cycle/DNA Replication, Immunology, Innate Immunity
Molecular Family
Adhesion Molecules
Antigen References
  1. Kim HRC, et al. 1999. Cancer Res. 59:4148
  2. Reljic R, et al. 2004. Immunol. Lett. 93:51.
  3. Takenaka Y et al. 2004. Mol. and Cell. Biol. 24:4395
  4. Joo GH, et al. 2001. J. Leukoc. Biol. 69:555
  5. Llinas L, et al. 2011. Immunol. Lett. 134:113-21
  6. Cabezón R, et al. 2011. Immunol. Lett. 134:167-73
Gene ID
16854 View all products for this Gene ID 3958 View all products for this Gene ID
UniProt
View information about Mac-2 on UniProt.org

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