PE anti-mouse/human Galectin-3 (Mac-2) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
200µg	￥ 335	1

Product Details

Verified Reactivity

Mouse, Human

Reported Reactivity

African Green, Baboon, Cynomolgus

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Human Recombinant (partial), amino acids 151-251

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.

Concentration

0.2 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per 10⁶ cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser

Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Application Notes

Based on immunogen information, clone Gal397 may recognize African Green Baboon and Cynomolgus. It is recommended to test the reagent for optimal performance for other species. Due to in-house testing, the purified format is not recommended for flow cytometry and intracellular flow cytometry.

Product Citations

Nielsen MA, et al. 2022. Front Immunol. 13:915890. PubMed
Zhang X, et al. 2016. J. Clin. Pathol.. 69:1100-1104. PubMed
Paz H, et al. 2018. J Exp Clin Cancer Res. 37:67. PubMed
Ramos-Medina R, et al. 2011. Immunol. Lett. 134:150-6. PubMed

RRID

AB_1134012 (BioLegend Cat. No. 126706)

Antigen Details

Structure

Human Galetcin-3 has 250 amino acids with a predicted molecular weight of 26 kD.
Mouse Galetcin-3 has 264 amino acids with a predicted molecular weight of 27.5 kD.

Distribution

Localized in the nucleus, cytoplasm, cell surface, or extracellular matrix. Expressed by tumor cells, monocytes/macrophages, epithelial cells, Kupffer cells, dendritic cells

Function

Regulate cell proliferation and differentiation, adhesion, anti-apoptosis

Ligand/Receptor

Variety ligands, such as IgE, IgA, galactose, casein kinase I, laminin, mucin, LAMPs, CD66, etc

Cell Type

Dendritic cells, Epithelial cells, Macrophages, Monocytes

Biology Area

Cell Adhesion, Cell Biology, Cell Cycle/DNA Replication, Immunology, Innate Immunity

Molecular Family

Adhesion Molecules

Antigen References

Kim HRC, et al. 1999. Cancer Res. 59:4148
Reljic R, et al. 2004. Immunol. Lett. 93:51.
Takenaka Y et al. 2004. Mol. and Cell. Biol. 24:4395
Joo GH, et al. 2001. J. Leukoc. Biol. 69:555
Llinas L, et al. 2011. Immunol. Lett. 134:113-21
Cabezón R, et al. 2011. Immunol. Lett. 134:167-73

Gene ID

16854 View all products for this Gene ID 3958 View all products for this Gene ID

UniProt

View information about Mac-2 on UniProt.org

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