Purified anti-human CD197 (CCR7) Antibody
- 产品名称：
- Purified anti-human CD197 (CCR7) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 353202
- 产品应用：
- 353202
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- CCR7-transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- Dubrovsky L, et al. 2020. MBio. 11:. PubMed
- Wagner J et al. 2019. Cell. 177(5):1330-1345 . PubMed
- Kaufmann M, et al. 2021. Med. 2(3):296-312.e8. PubMed
- Kondo H, et al. 2022. Front Immunol. 13:836923. PubMed
- O'Boyle KC, et al. 2020. Methods Mol Biol. 2111:1. PubMed
- Cobb DA, et al. 2022. J Immunother Cancer. 10:. PubMed
- Del Alcazar D, et al. 2019. Cell Rep. 28:3047. PubMed
- Li G, et al. 2022. Mol Ther Oncolytics. 24:887. PubMed
- Mishra A, et al. 2021. Cell. 184(13):3394-3409.e20. PubMed
- Schwabenland M, et al. 2021. Immunity. . PubMed
- De Maeyer RPH, et al. 2020. Nat Immunol. 21:615. PubMed
- RRID
- AB_10945157 (BioLegend Cat. No. 353202)
- Structure
- Chemokine receptor, G protein-coupled receptors (GPCR), seven transmembrane receptor.
- Distribution
-
T cells, B cells, NK, dendritic cells.
- Function
- The chemokine receptor CCR7 plays a pivotal role in the homing of na?ve T cells and regulatory T cells to secondary lymphoid organs, and the migration of dendritic cells into afferent lymphatic vessels.
- Ligand/Receptor
- CCL19 and CCL21.
- Cell Type
- B cells, Dendritic cells, NK cells, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Yanagihara S,?et al.?1998.?J. Immunol.?161:3096.
2. Charo IF,?et al.?2006.?N. Engl. J. Med.?354:610.
3. Reif K,?et al.?2002.?Nature?416:94.
4. Nakata B,?et al.?2008.?Oncology?74:69.
5.?Brodie T.?et al. 2013.?Cytometry A.?6: 530-2.?PubMed
6. Graves A.J. et al. 2014. Cytometry A. 7: 576–9?PubMed
7. Moncunill G. et al. 2014. Cytometry A. 12: 995-8?PubMed
- Gene ID
- 1236 View all products for this Gene ID
- UniProt
- View information about CD197 on UniProt.org
