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Purified anti-human CD197 (CCR7) (Maxpar® Read
产品名称:
Purified anti-human CD197 (CCR7) (Maxpar® Read
产品类别:
抗体
产品编号:
353237
产品应用:
353237
[价格]
规格 价格 库存
100µg ¥ 194 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
CCR7-transfected cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1.0 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
CyTOF? - Verified

Recommended Usage

This product is suitable for use with the?Maxpar? Metal Labeling Kits.?For metal labeling using Maxpar? Ready antibodies,?proceed directly to the step to Partially Reduce the Antibody by adding 100 ?l of Maxpar? Ready antibody to 100 ?l of 4 mM TCEP-R in a 50 kDa filter and continue with the protocol. Always refer to the latest version of Maxpar? User Guide when conjugating Maxpar? Ready antibodies.

Additional Product Notes

Maxpar? is a registered trademark of Standard BioTools Inc.

Product Citations
  1. Gide TN, et al. 2019. Cancer Cell. 35:238. PubMed
  2. Roussel M, et al. 2021. Cell Reports Medicine. 2(6):100291. PubMed
  3. Jordan S, et al. 2020. Cell. 178(5):1102-1114.e17.. PubMed
  4. Wimmers F, et al. 2021. Cell. 184:3915. PubMed
RRID
AB_2563726 (BioLegend Cat. No. 353237)

Antigen Details

Structure
Chemokine receptor, G protein-coupled receptors (GPCR), seven transmembrane receptor.
Distribution

T cells, B cells, NK, dendritic cells.

Function
The chemokine receptor CCR7 plays a pivotal role in the homing of na?ve T cells and regulatory T cells to secondary lymphoid organs, and the migration of dendritic cells into afferent lymphatic vessels.
Ligand/Receptor
CCL19 and CCL21.
Cell Type
B cells, Dendritic cells, NK cells, T cells
Biology Area
Immunology
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Yanagihara S,?et al.?1998.?J. Immunol.?161:3096.
2. Charo IF,?et al.?2006.?N. Engl. J. Med.?354:610.
3. Reif K,?et al.?2002.?Nature?416:94.
4. Nakata B,?et al.?2008.?Oncology?74:69.
5.?Brodie T.?et al. 2013.?Cytometry A.?6: 530-2.?PubMed
6. Graves A.J. et al. 2014. Cytometry A. 7: 576–9?PubMed
7. Moncunill G. et al. 2014. Cytometry A. 12: 995-8?PubMed

Gene ID
1236 View all products for this Gene ID
UniProt
View information about CD197 on UniProt.org

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