PerCP/Cyanine5.5 anti-human CD197 (CCR7) Antibody
- 产品名称：
- PerCP/Cyanine5.5 anti-human CD197 (CCR7) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 353219
- 产品应用：
- 353219
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- CCR7-transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.
- Excitation Laser
- Blue Laser (488 nm)
- Additional Product Notes
BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.
- Product Citations
-
- Zhang S, et al. 2015. J Virol. 89: 8304-8317. PubMed
- Liu B, et al. 2015. J Virol. 89: 11834 - 11844. PubMed
- Henault J, et al. 2015. Nat Immunol. 17: 196-203. PubMed
- Kwiecie? I, et al. 2020. Cells. 9:00. PubMed
- Karim F, et al. 2021. Elife. 10:. PubMed
- Anft M, et al. 2021. J Nephrol. 6:. PubMed
- Rutkowska E, et al. 2021. Cells. 10:. PubMed
- Weiskopf D, et al. 2015. J Virol. 89:120. PubMed
- Nagafuchi Y, et al. 2016. Sci Rep. 6:29338. PubMed
- Chiarini M, et al. 2012. Mult Scler. 1.297222222. PubMed
- Arlehamn C, et al. 2016. PLoS Pathog. 12: 1005760. PubMed
- Jensen S, et al. 2015. PLoS One. 10: e0139573. PubMed
- Weiskopf D, et al. 2015. Proc Natl Acad Sci U S A. 112: E4256-E4263. PubMed
- Arlehamn C, et al. 2014. J Immunol. 193:2931. PubMed
- Tian Y, et al. 2019. Cell Rep. 29:4482. PubMed
- Seo IH, et al. 2021. Immune Netw. 21:e17. PubMed
- Démoulins T, et al. 2014. Nanomedicine. 10:1739. PubMed
- Wang J, et al. 2020. Cancer Immunol Res. 794:8. PubMed
- Jung JH, et al. 2021. Nat Commun. 12:4043. PubMed
- Seumois G, et al. 2016. J Immunol. 197: 655 - 664. PubMed
- Cohen CA, et al. 2021. Nat Commun. 12:4678. PubMed
- Bhattacharya P, et al. 2020. Elife. 9:00. PubMed
- Hurton L, et al. 2016. Proc Natl Acad Sci U S A. 113: E7788 - E7797. PubMed
- Lundy SK, et al. 2018. Front Med (Lausanne). 0.38125. PubMed
- Nakachi S, et al. 2017. Arthritis Research & Therapy . 10.1186/s13075-017-1309-x. PubMed
- Burel JG, et al. 2019. Elife. 8. PubMed
- Thieme CJ, et al. 2020. Cell Rep Med. 1:100092. PubMed
- Luetke-Eversloh M, et al. 2014. PLoS Pathog. 10:1004441. PubMed
- Jensen S, et al. 2015. PLoS One. 10: 0145249. PubMed
- Seo IH, et al. 2021. Cell Reports. 36(4):109438. PubMed
- Delmas A, et al. 2016. PLoS One. 11: 0163305. PubMed
- Alwis R, et al. 2016. J Virol. 90: 4771 - 4779. PubMed
- Kwiecien I, et al. 2022. Front Immunol. 13:864497. PubMed
- Havenith S, et al. 2012. Int Immunol. 24:625. PubMed
- Lamichhane R et al. 2019. Cell Rep. 28(12):3061-3076 . PubMed
- RRID
- AB_10915275 (BioLegend Cat. No. 353219) AB_10916121 (BioLegend Cat. No. 353220)
- Structure
- Chemokine receptor, G protein-coupled receptors (GPCR), seven transmembrane receptor.
- Distribution
-
T cells, B cells, NK, dendritic cells.
- Function
- The chemokine receptor CCR7 plays a pivotal role in the homing of na?ve T cells and regulatory T cells to secondary lymphoid organs, and the migration of dendritic cells into afferent lymphatic vessels.
- Ligand/Receptor
- CCL19 and CCL21.
- Cell Type
- B cells, Dendritic cells, NK cells, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Yanagihara S,?et al.?1998.?J. Immunol.?161:3096.
2. Charo IF,?et al.?2006.?N. Engl. J. Med.?354:610.
3. Reif K,?et al.?2002.?Nature?416:94.
4. Nakata B,?et al.?2008.?Oncology?74:69.
5.?Brodie T.?et al. 2013.?Cytometry A.?6: 530-2.?PubMed
6. Graves A.J. et al. 2014. Cytometry A. 7: 576–9?PubMed
7. Moncunill G. et al. 2014. Cytometry A. 12: 995-8?PubMed
- Gene ID
- 1236 View all products for this Gene ID
- UniProt
- View information about CD197 on UniProt.org
