PE/Dazzle™ 594 anti-human CD197 (CCR7) Antib
- 产品名称：
- PE/Dazzle™ 594 anti-human CD197 (CCR7) Antib
- 产品类别：
- 抗体
- 产品编号：
- 353235
- 产品应用：
- 353235
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- CCR7-transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Dazzle? 594 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
* PE/Dazzle? 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Product Citations
-
- Argüello RJ, et al. 2020. Cell Metab. 32:1063. PubMed
- Jiguet-Jiglaire C, et al. 2022. Acta Neuropathol Commun. 10:1. PubMed
- Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
- Neidleman J, et al. 2020. Elife. 9:00. PubMed
- Torres-Ruiz J, et al. 2021. Front Immunol. 12:689966. PubMed
- Lerrer S, et al. 2021. iScience. 24:103020. PubMed
- Fenton TM, et al. 2020. Immunity. 52(3):557-570. PubMed
- Passaes C, et al. 2020. Cell Rep. 32:108174. PubMed
- Messinger JE, et al. 2019. MBio. 10. PubMed
- Menges D, et al. 2022. Nat Commun. 13:4855. PubMed
- FitzPatrick MEB, et al. 2021. Cell Rep. 34:108661. PubMed
- Duhen R, et al. 2021. Nat Commun. 12:1047. PubMed
- Xie G, et al. 2021. Cell Reports. 35(4):109038. PubMed
- Salumets A, et al. 2022. Aging Cell. 21:e13607. PubMed
- Peng Y, et al. 2020. Nat Immunol. 1.802777778. PubMed
- RRID
- AB_2563640 (BioLegend Cat. No. 353235) AB_2563641 (BioLegend Cat. No. 353236)
- Structure
- Chemokine receptor, G protein-coupled receptors (GPCR), seven transmembrane receptor.
- Distribution
-
T cells, B cells, NK, dendritic cells.
- Function
- The chemokine receptor CCR7 plays a pivotal role in the homing of na?ve T cells and regulatory T cells to secondary lymphoid organs, and the migration of dendritic cells into afferent lymphatic vessels.
- Ligand/Receptor
- CCL19 and CCL21.
- Cell Type
- B cells, Dendritic cells, NK cells, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Yanagihara S,?et al.?1998.?J. Immunol.?161:3096.
2. Charo IF,?et al.?2006.?N. Engl. J. Med.?354:610.
3. Reif K,?et al.?2002.?Nature?416:94.
4. Nakata B,?et al.?2008.?Oncology?74:69.
5.?Brodie T.?et al. 2013.?Cytometry A.?6: 530-2.?PubMed
6. Graves A.J. et al. 2014. Cytometry A. 7: 576–9?PubMed
7. Moncunill G. et al. 2014. Cytometry A. 12: 995-8?PubMed
- Gene ID
- 1236 View all products for this Gene ID
- UniProt
- View information about CD197 on UniProt.org
