PE anti-human CD197 (CCR7) Antibody
- 产品名称：
- PE anti-human CD197 (CCR7) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 353203
- 产品应用：
- 353203
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- CCR7-transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Product Citations
-
- Aschmoneit N, et al. 2021. J Immunother Cancer. 9:. PubMed
- Rendeiro AF, et al. 2020. Nat Commun. 11:577. PubMed
- Li M, et al. 2022. Sci Rep. 12:378. PubMed
- Zeng W, et al. 2017. Front Immunol. 0.806944444. PubMed
- Zhou R, et al. 2020. Immunity. S1074-7613(20)30333-2.. PubMed
- Acharya N, et al. 2020. Immunity. 53(3):658-671.e6. PubMed
- Kubo M, et al. 2018. Oncol Rep. 39:417. PubMed
- Kramer KJ, et al. 2022. Nat Commun. 13:3466. PubMed
- Xiong X, et al. 2021. Liver Int. 41:1033. PubMed
- Cappellano G, et al. 2018. PLoS One. 13:e0192108. PubMed
- Kang L, et al. 2020. Exp Hematol Oncol. 9:11. PubMed
- Tatovic D, et al. 2015. J Immunol. 195: 386 - 392. PubMed
- Zhang X, et al. 2021. Nat Commun. 12:5291. PubMed
- Gullà A, et al. 2021. Cancer Discov. . PubMed
- Aschmoneit N, et al. 2022. Oncoimmunology. 11:2028961. PubMed
- Balan I, et al. 2022. Front Immunol. 13:940095. PubMed
- Kuo HH, et al. 2018. Immunity. 48:1183. PubMed
- Alhaj Hussen K, et al. 2017. Immunity. 47:680. PubMed
- Ahmad S,et al. 2017. Prog Neuropsychopharmacol Biol Psychiatry. . 10.1016/j.pnpbp.2017.10.001. PubMed
- Wu J et al. 2019. Immunity. 50(5):1218-1231 . PubMed
- Magri G et al. 2017. Immunity. 47(1):118-134 . PubMed
- Aschmoneit N, et al. 2021. Sci Rep. 11:13880. PubMed
- Vadrevu KM, et al. 2022. Sci Rep. 12:12038. PubMed
- Borowicz S, et al. 2021. PLOS ONE. 16(6):e0252197. PubMed
- Usmani SM et al. 2019. Cell host & microbe. 25(1):73-86 . PubMed
- Christiansen M, et al. 2020. Front Immunol. 10:3022. PubMed
- Tavira B, et al. 2018. J Diabetes Res. 2018:9391845. PubMed
- Audigé A, et al. 2017. BMC Immunology. 10.1186/s12865-017-0209-9. PubMed
- Ramos MIP, et al. 2021. Elife. 10:. PubMed
- Hirschberger S, et al. 2021. EMBO Mol Med. 13:e14323. PubMed
- Collins PL et al. 2018. Cell. 176(1-2):348-360 . PubMed
- Chen Y, et al. 2020. Cell. 1496:183. PubMed
- Montel‐Hagen A et al. 2019. Cell stem cell. 24(3):376-389 . PubMed
- Gullà A, et al. 2021. Cancer Discov. 2:468. PubMed
- Chen R, et al. 2021. Front Oncol. 11:743050. PubMed
- Gamradt S, et al. 2021. iScience. 24:103312. PubMed
- RRID
- AB_10916391 (BioLegend Cat. No. 353203) AB_10913813 (BioLegend Cat. No. 353204)
- Structure
- Chemokine receptor, G protein-coupled receptors (GPCR), seven transmembrane receptor.
- Distribution
-
T cells, B cells, NK, dendritic cells.
- Function
- The chemokine receptor CCR7 plays a pivotal role in the homing of na?ve T cells and regulatory T cells to secondary lymphoid organs, and the migration of dendritic cells into afferent lymphatic vessels.
- Ligand/Receptor
- CCL19 and CCL21.
- Cell Type
- B cells, Dendritic cells, NK cells, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Yanagihara S,?et al.?1998.?J. Immunol.?161:3096.
2. Charo IF,?et al.?2006.?N. Engl. J. Med.?354:610.
3. Reif K,?et al.?2002.?Nature?416:94.
4. Nakata B,?et al.?2008.?Oncology?74:69.
5.?Brodie T.?et al. 2013.?Cytometry A.?6: 530-2.?PubMed
6. Graves A.J. et al. 2014. Cytometry A. 7: 576–9?PubMed
7. Moncunill G. et al. 2014. Cytometry A. 12: 995-8?PubMed
- Gene ID
- 1236 View all products for this Gene ID
- UniProt
- View information about CD197 on UniProt.org
