FITC anti-human CD197 (CCR7) Antibody
- 产品名称：
- FITC anti-human CD197 (CCR7) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 353215
- 产品应用：
- 353215
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- CCR7-transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
- Additional Product Notes
View more applications data for this product in our Scientific Poster Library.
- Product Citations
-
- Adams S, et al. 2012. Clin Cancer Res. 18:6748. PubMed
- Conforti A, et al. 2021. PLoS One. 16:e0259894. PubMed
- Li H, et al. 2016. J Immunol. 196: 4064 - 4074. PubMed
- Hearnden R, et al. 2021. STAR Protocols. 2(2):100422. PubMed
- Zebley CC, et al. 2021. Cell Rep. 37:109796. PubMed
- Vanshylla K, et al. 2022. Cell Host Microbe. 30:69. PubMed
- Rubio-Pérez C, et al. 2021. Nat Commun. 1503:12. PubMed
- Dan H, et al. 2020. Mol Oncol. 14:795. PubMed
- Tarke A, et al. 2021. Cell Reports Medicine. 2(7):100355. PubMed
- Peluso MJ, et al. 2021. Cell Rep. 36:109518. PubMed
- Kim D, et al. 2020. Nat Med. 26:236. PubMed
- Rebou?as A, et al. 2021. Microorganisms. 9:. PubMed
- Zebley CC, et al. 2021. Cell Rep. 37:110079. PubMed
- Mudd PA, et al. 2022. Cell. 185:603. PubMed
- Yu ED, et al. 2022. Cell Host Microbe. 30:1269. PubMed
- Einkauf KB, et al. 2019. J Clin Invest. 129:988. PubMed
- Einkauf KB, et al. 2022. Cell. 185:266. PubMed
- Jiang C, et al. 2020. Nature. 261:585. PubMed
- Lazarski CA, et al. 2020. Cytotherapy. . PubMed
- Sehgal R, et al. 2022. Front Immunol. 13:828949. PubMed
- Schouest B, et al. 2021. J Virol. 95:. PubMed
- Fu Y, et al. 2021. Cell Reports. 36(2):109344. PubMed
- Qin H, et al. 2015. Blood. 126: 629 - 639. PubMed
- Rousso-Noori L, et al. 2021. Nat Commun. 12:3615. PubMed
- Hackstein CP, et al. 2022. Nat Commun. 13:7472. PubMed
- Wang B, et al. 2018. Mol Ther Nucleic Acids. 0.548611111. PubMed
- Yu ED, et al. 2022. Cell Host Microbe. . PubMed
- Sasawatari S, et al. 2020. J Immunol. 1373:204. PubMed
- Hu W, et al. 2022. Mater Today Bio. 14:100224. PubMed
- RRID
- AB_10945291 (BioLegend Cat. No. 353215) AB_10916386 (BioLegend Cat. No. 353216)
- Structure
- Chemokine receptor, G protein-coupled receptors (GPCR), seven transmembrane receptor.
- Distribution
-
T cells, B cells, NK, dendritic cells.
- Function
- The chemokine receptor CCR7 plays a pivotal role in the homing of na?ve T cells and regulatory T cells to secondary lymphoid organs, and the migration of dendritic cells into afferent lymphatic vessels.
- Ligand/Receptor
- CCL19 and CCL21.
- Cell Type
- B cells, Dendritic cells, NK cells, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Yanagihara S,?et al.?1998.?J. Immunol.?161:3096.
2. Charo IF,?et al.?2006.?N. Engl. J. Med.?354:610.
3. Reif K,?et al.?2002.?Nature?416:94.
4. Nakata B,?et al.?2008.?Oncology?74:69.
5.?Brodie T.?et al. 2013.?Cytometry A.?6: 530-2.?PubMed
6. Graves A.J. et al. 2014. Cytometry A. 7: 576–9?PubMed
7. Moncunill G. et al. 2014. Cytometry A. 12: 995-8?PubMed
- Gene ID
- 1236 View all products for this Gene ID
- UniProt
- View information about CD197 on UniProt.org
