APC/Cyanine7 anti-human CD197 (CCR7) Antibody
- 产品名称：
- APC/Cyanine7 anti-human CD197 (CCR7) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 353211
- 产品应用：
- 353211
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- CCR7-transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Additional Product Notes
BioLegend is in the process of converting the name APC/Cy7 to APC/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our APC/Cyanine7 products. Please contact Technical Service if you have any questions.
- Product Citations
-
- Mo Y, et al. 2022. Front Immunol. 12:799896. PubMed
- Meng Q, et al. 2016. PLoS One. 11:e0166954. PubMed
- Wu VH, et al. 2020. JCI Insight. 5:00. PubMed
- Xiao C, et al. 2022. iScience. 25:103934. PubMed
- Kim C, et al. 2018. Cell Rep. 25:2148. PubMed
- Tauriainen J, et al. 2017. Sci Rep. 7:40354. PubMed
- Hinks TSC, et al. 2019. Cell Rep. 28:3249. PubMed
- Kuri-Cervantes L, et al. 2020. STAR Protoc. 1:100154. PubMed
- Demers K, et al. 2016. PLoS Pathog. 12: 1005805. PubMed
- Hong J, et al. 2014. J Immunol. 193:797. PubMed
- Uchtenhagen H, et al. 2016. Nat Commun. 7:12614. PubMed
- Alrubayyi A, et al. 2021. Nat Commun. 12:5839. PubMed
- Jankeel A, et al. 2020. J Virol. :94. PubMed
- Japp AS, et al. 2021. Cell. 184(3):827-839.e14. PubMed
- Kuo HH, et al. 2018. Immunity. 48:1183. PubMed
- Kim C, et al. 2019. Cell Rep. 29:2202. PubMed
- Xu S, et al. 2021. Immunity. . PubMed
- Pattekar A, et al. 2021. Cellular and Molecular Gastroenterology and Hepatology. 11(5):1267-1289. PubMed
- Buggert M, et al. 2020. Cell. 183(7):1946-1961.e15. PubMed
- Colomb F, et al. 2020. Cell Reports. 32(5):107991. PubMed
- Gao Y, et al. 2022. Immunity. 55:1732. PubMed
- Krishnan S, et al. 2021. Clin Exp Immunol. 203:458. PubMed
- Poon MML, et al. 2021. Cell Rep. 37:110071. PubMed
- Rasmussen TA, et al. 2022. Cell Rep Med. 3:100766. PubMed
- Le J, et al. 2020. Immunity. 52(6):1105-1118.e9. PubMed
- Sekine T, et al. 2020. Cell. 183:158. PubMed
- NULL, et al. 2022. Cell. 185:916. PubMed
- Shuwa HA, et al. 2021. Med. 2(6):720-735.e4. PubMed
- Meijgaarden K, et al. 2015. PLoS Pathog. 11:1004671. PubMed
- Crump NT, et al. 2021. Cell Reports. 35(6):109101. PubMed
- Katsuyama E, et al. 2020. Cell Reports. 30(1):112-123.e4.. PubMed
- Rusconi M, et al. 2017. Sci Rep. 5.745138889. PubMed
- Cortés–Rubio CN, et al. 2019. Clin Epigenetics. 11:134. PubMed
- RRID
- AB_10915272 (BioLegend Cat. No. 353211) AB_10916390 (BioLegend Cat. No. 353212)
- Structure
- Chemokine receptor, G protein-coupled receptors (GPCR), seven transmembrane receptor.
- Distribution
-
T cells, B cells, NK, dendritic cells.
- Function
- The chemokine receptor CCR7 plays a pivotal role in the homing of na?ve T cells and regulatory T cells to secondary lymphoid organs, and the migration of dendritic cells into afferent lymphatic vessels.
- Ligand/Receptor
- CCL19 and CCL21.
- Cell Type
- B cells, Dendritic cells, NK cells, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Yanagihara S,?et al.?1998.?J. Immunol.?161:3096.
2. Charo IF,?et al.?2006.?N. Engl. J. Med.?354:610.
3. Reif K,?et al.?2002.?Nature?416:94.
4. Nakata B,?et al.?2008.?Oncology?74:69.
5.?Brodie T.?et al. 2013.?Cytometry A.?6: 530-2.?PubMed
6. Graves A.J. et al. 2014. Cytometry A. 7: 576–9?PubMed
7. Moncunill G. et al. 2014. Cytometry A. 12: 995-8?PubMed
- Gene ID
- 1236 View all products for this Gene ID
- UniProt
- View information about CD197 on UniProt.org
