APC anti-human CD197 (CCR7) Antibody
- 产品名称：
- APC anti-human CD197 (CCR7) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 353213
- 产品应用：
- 353213
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- CCR7-transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Product Citations
-
- Li M, et al. 2021. J Clin Invest. 131:. PubMed
- Andonian BJ, et al. 2022. Sci Rep. 12:7450. PubMed
- Shen Y, et al. 2021. Cell Stress Chaperones. 26:937. PubMed
- Muliaditan T, et al. 2021. Cell Rep Med. 2:100457. PubMed
- Chiu YL, et al. 2018. Immun Ageing. 15:27. PubMed
- Blengio F, et al. 2013. Immunobiology. 218:76. PubMed
- Liu C, et al. 2021. Cell Res. 31:1106. PubMed
- Guo J, et al. 2022. Front Cell Dev Biol. 9:775599. PubMed
- Fajgenbaum DC, et al. 2019. J Clin Invest. 130:4451. PubMed
- Jo T, et al. 2022. Cancer Immunol Immunother. Online ahead of print. PubMed
- Miao L, et al. 2021. Clin Transl Med. 11:e395. PubMed
- Mao FY, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:395. PubMed
- Luo Y, et al. 2021. Nat Commun. 12:3913. PubMed
- Cho JH, et al. 2021. Nat Commun. 12:792. PubMed
- Dai X, et al. 2021. Bioact Mater. 1.659027778. PubMed
- Soriano-Sarabia N, et al. 2014. J Virol. 88:14070. PubMed
- Yin S, et al. 2015. Sci Rep. 5: 14432. PubMed
- Bradley T et al. 2018. Cell reports. 25(1):107-117 . PubMed
- Koh WH, et al. 2020. STAR Protoc. 1:100203. PubMed
- Ronaghan NJ, et al. 2022. PLoS One. 17:e0276013. PubMed
- Mysore V, et al. 2021. Med (N Y). 2:1050. PubMed
- RRID
- AB_10915474 (BioLegend Cat. No. 353213) AB_10917387 (BioLegend Cat. No. 353214)
- Structure
- Chemokine receptor, G protein-coupled receptors (GPCR), seven transmembrane receptor.
- Distribution
-
T cells, B cells, NK, dendritic cells.
- Function
- The chemokine receptor CCR7 plays a pivotal role in the homing of na?ve T cells and regulatory T cells to secondary lymphoid organs, and the migration of dendritic cells into afferent lymphatic vessels.
- Ligand/Receptor
- CCL19 and CCL21.
- Cell Type
- B cells, Dendritic cells, NK cells, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Yanagihara S,?et al.?1998.?J. Immunol.?161:3096.
2. Charo IF,?et al.?2006.?N. Engl. J. Med.?354:610.
3. Reif K,?et al.?2002.?Nature?416:94.
4. Nakata B,?et al.?2008.?Oncology?74:69.
5.?Brodie T.?et al. 2013.?Cytometry A.?6: 530-2.?PubMed
6. Graves A.J. et al. 2014. Cytometry A. 7: 576–9?PubMed
7. Moncunill G. et al. 2014. Cytometry A. 12: 995-8?PubMed
- Gene ID
- 1236 View all products for this Gene ID
- UniProt
- View information about CD197 on UniProt.org
