PE anti-human CD183 (CXCR3) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 153	1

Product Details

Verified Reactivity

Human, Cynomolgus, Rhesus

Reported Reactivity

African Green, Baboon

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Human CXCR3 transfectants

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser

Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Product Citations

Biasci D, et al. 2020. Proc Natl Acad Sci U S A. 117:28960. PubMed
Ivan Jelcic et al. 2018. Cell. 175(1):85-100 . PubMed
Li H, et al. 2016. J Immunol. 196: 4064 - 4074. PubMed
Kim CJ, et al. 2018. Immunity. 49:1034. PubMed
Pein M, et al. 2020. Nat Commun. 11:1494. PubMed
Imai Y, et al. 2021. JID Innov. 1:100003. PubMed
Lam AJ, et al. 2021. Cell Reports. 36(5):109494. PubMed
Alexander T, et al. 2013. Ann Rheum Dis. 72:1549. PubMed
Martín–Gayo E, et al. 2020. Cell Rep. 30:984. PubMed
Hunter S, et al. 2018. J Hepatol. 69:654. PubMed
Bhattacharya P, et al. 2020. Elife. 9:00. PubMed
Gorman JA, et al. 2019. Front Immunol. 10:44. PubMed
Hirschberger S, et al. 2021. EMBO Mol Med. 13:e14323. PubMed
Wang W, et al. 2019. Cell Rep. 28:486. PubMed
Szodoray P, et al. 2021. Cell Reports. 36(6):109525. PubMed
Eckert EC, et al. 2020. Mol Ther Oncolytics. 0.710416667. PubMed
Gamradt S, et al. 2021. iScience. 24:103312. PubMed

RRID

AB_10959652 (BioLegend Cat. No. 353705) AB_10962912 (BioLegend Cat. No. 353706)

Antigen Details

Structure: CXC-chemokine receptor, G protein-coupled receptor, seven-pass transmembrane receptor
Distribution: T cell subset, NK cells, plasmacytoid dendritic cells, GM-CSF activated CD34⁺ hematopoietic progenitors, mast cells, alveolar macrophages, eosinophils, and airway epithelial cells
Function: Essential in T cell recruitment to sites of inflammation
Ligand/Receptor: CXCL9, CXCL10, and CXCL11
Cell Type: Dendritic cells, Eosinophils, Epithelial cells, Hematopoietic stem and progenitors, Macrophages, Mast cells, NK cells, T cells, Tregs
Biology Area: Cell Biology, Immunology, Neuroinflammation, Neuroscience
Molecular Family: CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References: 1. Loetscher M, et al. 1996. J. Exp. Med. 184:963.
2. Cole KE, et al. 1998. J. Exp. Med. 187:2009.
3. Aksoy MO, et al. 2006. Am. J. Physiol. Lung Cell Mol. Physiol. 290:L909.
4. Curbishley SM, et al. 2005. Am. J. Pathol. 167:887.
5. Turner JE, et al. 2007. Mini. Rev. Med. Chem. 7:1089.
6. Wenzel J, et al. 2008. J. Invest. Dermatol. 128:67.
Gene ID: 2833 View all products for this Gene ID
UniProt: View information about CD183 on UniProt.org

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