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Purified anti-BRST-2 (GCDFP-15) Antibody
产品名称:
Purified anti-BRST-2 (GCDFP-15) Antibody
产品类别:
抗体
产品编号:
915106
产品应用:
915106
[价格]
规格 价格 库存
100µg ¥ 229 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
This antibody was generated against Gross Cystic Disease Fluid Protein 15.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

IHC-P - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 0.1 - 1.0 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

The BRST-2 clone D6 recognizes a 15 kD glycoprotein known as Gross Cystic Disease Fluid Protein-15 (GCDFP-15). Antigen retrieval is not required. The BRST-2 epitope is heat-sensitive; paraffin sections that have been heat fixed at 60°C may lose antibody binding sites.

Application References

(PubMed link indicates BioLegend citation)
  1. Yoshimura Y, et al. 2011. Jpn. J. Clin. Oncol. 41:358. (IHC) PubMed
  2. Fan CY, et al. 2000. Am. J. Surg. Pathol. 24(4):579. PubMed
  3. Wick MR, et al. 1989. Hum. Pathol. 20(3):281. PubMed
  4. Mazoujian G, et al. 1984. Am. J. Surg. Pathol. 8(1):43. PubMed
  5. Mazoujian G, et al. 1983. Am. J. Pathol. 110:105. PubMed
  6. Brown RW, et al. 1997. Am. J. Clin. Path. 107:12. PubMed
RRID
AB_2616964 (BioLegend Cat. No. 915106)

Antigen Details

Structure
BRST-2 (GCDFP-15) is a 17 kD protein.
Distribution

Extracellular and nucleus.

Function
Diseases associated with BRST-2 include florid papillomatosis of the nipple and breast signet ring cell adenocarcinoma. Interacts with AZGP1.
Biology Area
Cancer Biomarkers, Cell Biology
Gene ID
5304 View all products for this Gene ID
UniProt
View information about BRST-2 on UniProt.org

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