Purified anti-mouse CD206 (MMR) Antibody
- 产品名称：
- Purified anti-mouse CD206 (MMR) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 141701
- 产品应用：
- 141701
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant mouse CD206 (MMR)
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
ICFC - Quality tested
FC - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone C068C2 recognizes a region similar to clone MR5D3, based on the ability of the clones to block each other. Additional reported applications (for the relevant formats) include: spatial biology (IBEX)4,5.
- Application References
(PubMed link indicates BioLegend citation) -
- Keller J, et al. 2012. Biochem Biophys Res Commun. 417:217. PubMed
- Ito H, et al. 2012. J Am Soc Nephrol. 23:1797. PubMed
- Yang X, et al. 2015. PNAS. 112:2900. PubMed
- Radtke?AJ,?et al.?2020.?Proc Natl Acad Sci U S A.?117:33455-65. (SB)?PubMed
- Radtke?AJ,?et al.?2022.?Nat Protoc.?17:378-401. (SB)?PubMed
- Product Citations
-
- Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
- Loyher PL, et al. 2018. J Exp Med. 215:2536. PubMed
- Wang W, et al. 2018. Cancer Cell. 34:757. PubMed
- Dasgupta D, et al. 2020. Gastroenterology. 159:1487. PubMed
- Zappasodi R, et al. 2021. Nature. 591:652. PubMed
- Hilligan KL, et al. 2020. Nat Commun. 11:5637. PubMed
- Nolin JD, et al. 2017. JCI Insight. 2:e94929. PubMed
- Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
- Bisht K, et al. 2021. Nat Commun. 12:5289. PubMed
- Sun KT, et al. 2018. Front Physiol. 1.06875. PubMed
- Hu G, et al. 2021. Nat Commun. 12:773. PubMed
- Enders M, et al. 2020. J Immunol. 204:87. PubMed
- Tian Z, et al. 2022. Front Integr Neurosci. 15:742377. PubMed
- Dong Y, et al. 2020. Front Immunol. 11:29. PubMed
- Blriot C, et al. 2021. Immunity. :. PubMed
- Gubin MM, et al. 2018. Cell. 175:1014. PubMed
- Campesato LF, et al. 2020. Nat Commun. 3.24375. PubMed
- Yang X, et al. 2015. Proc Natl Acad Sci U S A. 112:2900. PubMed
- Kim D, et al. 2019. Immune Netw. 19:e32. PubMed
- Scortegagna M, et al. 2020. Nat Commun. 11:99. PubMed
- Wang G, et al. 2019. Front Immunol. 1.380555556. PubMed
- Pushalkar S, et al. 2018. Cancer Discov. 0.613194444. PubMed
- Kikuchi K, et al. 2018. J Immunol. 201:635. PubMed
- RRID
- AB_10900263 (BioLegend Cat. No. 141701) AB_10900233 (BioLegend Cat. No. 141702)
- Structure
- Type I transmembrane protein, 175 kD, C-type lectin superfamily
- Distribution
-
Macrophages, dendritic cells, Langerhans cells, liver endothelial cells
- Function
- Pathogen recognition, endocytosis and phagocytosis, antigen presentation
- Ligand/Receptor
- Antigen containing mannose, fucose, or an N-acetyl glucosamine
- Cell Type
- Dendritic cells, Endothelial cells, Langerhans cells, Macrophages
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Signal Transduction
- Molecular Family
- CD Molecules
- Antigen References
-
1. Wileman TE, et al. 1986. P. Natl. Acad. Sci. USA 83:2501.
2. Apostolopoulos V, et al. 2001. Curr. Mol. Med. 1:469.
3. Burgdorf S, et al. 2006. J. Immunol. 176:6770.
4. McKenzie EJ, et al. 2007. J. Immunol. 178:4975.
- Gene ID
- 17533 View all products for this Gene ID
- UniProt
- View information about CD206 on UniProt.org
