PerCP/Cyanine5.5 anti-mouse CD206 (MMR) Antibody
- 产品名称：
- PerCP/Cyanine5.5 anti-mouse CD206 (MMR) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 141715
- 产品应用：
- 141715
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant mouse CD206 (MMR)
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICFC - Quality tested
FC - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.
- Application Notes
Clone C068C2 recognizes a region similar to clone MR5D3, based on the ability of the clones to block each other. Additional reported applications (for the relevant formats) include: spatial biology (IBEX)4,5.
- Additional Product Notes
- BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Keller J, et al. 2012. Biochem Biophys Res Commun. 417:217. PubMed
- Ito H, et al. 2012. J Am Soc Nephrol. 23:1797. PubMed
- Yang X, et al. 2015. PNAS. 112:2900. PubMed
- Radtke?AJ,?et al.?2020.?Proc Natl Acad Sci U S A.?117:33455-65. (SB)?PubMed
- Radtke?AJ,?et al.?2022.?Nat Protoc.?17:378-401. (SB)?PubMed
- Product Citations
-
- Yang C, et al. 2022. Nat Commun. 13:3426. PubMed
- Lin C, et al. 2020. Cancer Immunol Res. 632:8. PubMed
- Morfoisse F, et al. 2018. Arterioscler Thromb Vasc Biol. 38:1346. PubMed
- Wang S, et al. 2022. Front Immunol. 13:869061. PubMed
- Zhao J, et al. 2022. J Nanobiotechnology. 20:62. PubMed
- Yerneni SS, et al. 2021. MBio. 12:e0165721. PubMed
- Wang C, et al. 2021. Cell Rep. 37:110021. PubMed
- An YA et al. 2017. eLife. 6 pii: e24071. PubMed
- Gao H, et al. 2021. Cells. 10:. PubMed
- Ano Y, et al. 2017. J Biol Chem. 292:3720. PubMed
- Gozgit JM, et al. 2021. Cancer Cell. :. PubMed
- Peng K, et al. 2017. PLoS One.. 10.1371/journal.pone.0183271. PubMed
- De Santi C, et al. 2022. Mol Ther Nucleic Acids. 29:643. PubMed
- Uddin MJ, et al. 2022. Mucosal Immunol. 15:165. PubMed
- Barsoumian HB, et al. 2020. J Immunother Cancer. 8:00. PubMed
- Oguri Y, et al. 2020. Cell. 182(3):563-577.e20. PubMed
- Xiao Y, et al. 2022. Nat Commun. 13:758. PubMed
- Bronisz–Budzynska I, et al. 2019. Skelet Muscle. 9:22. PubMed
- Shigeta A, et al. 2019. Dev Cell. 48:617. PubMed
- Zhang Z, et al. 2020. Front Immunol. 11:583276. PubMed
- Chao Y, et al. 2020. Sci Adv. 6:eaaz4204. PubMed
- Zhou Y, et al. 2022. Theranostics. 12:5488. PubMed
- Barsoumian HB, et al. 2022. Cancers (Basel). 14:. PubMed
- Li Z, et al. 2022. Evid Based Complement Alternat Med. 2022:7421265. PubMed
- Yang C, et al. 2019. J Transl Med. 1.004166667. PubMed
- Calvente CJ, et al. 2019. J Clin Invest. 130:4091. PubMed
- Wang C, et al. 2020. Mucosal Immunol. 13:22. PubMed
- Zhang J, et al. 2020. Cell Metabolism. 31(6):1136-1153. PubMed
- Cortez MA, et al. 2020. Nat Commun. 3.819444444. PubMed
- RRID
- AB_2561991 (BioLegend Cat. No. 141715) AB_2561992 (BioLegend Cat. No. 141716)
- Structure
- Type I transmembrane protein, 175 kD, C-type lectin superfamily
- Distribution
-
Macrophages, dendritic cells, Langerhans cells, liver endothelial cells
- Function
- Pathogen recognition, endocytosis and phagocytosis, antigen presentation
- Ligand/Receptor
- Antigen containing mannose, fucose, or an N-acetyl glucosamine
- Cell Type
- Dendritic cells, Endothelial cells, Langerhans cells, Macrophages
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Signal Transduction
- Molecular Family
- CD Molecules
- Antigen References
-
1. Wileman TE, et al. 1986. P. Natl. Acad. Sci. USA 83:2501.
2. Apostolopoulos V, et al. 2001. Curr. Mol. Med. 1:469.
3. Burgdorf S, et al. 2006. J. Immunol. 176:6770.
4. McKenzie EJ, et al. 2007. J. Immunol. 178:4975.
- Gene ID
- 17533 View all products for this Gene ID
- UniProt
- View information about CD206 on UniProt.org
