PE/Cyanine7 anti-mouse CD206 (MMR) Antibody
- 产品名称：
- PE/Cyanine7 anti-mouse CD206 (MMR) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 141719
- 产品应用：
- 141719
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant mouse CD206 (MMR)
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICFC - Quality tested
FC - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Clone C068C2 recognizes a region similar to clone MR5D3, based on the ability of the clones to block each other. Additional reported applications (for the relevant formats) include: spatial biology (IBEX)4,5.
- Additional Product Notes
- BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Keller J, et al. 2012. Biochem Biophys Res Commun. 417:217. PubMed
- Ito H, et al. 2012. J Am Soc Nephrol. 23:1797. PubMed
- Yang X, et al. 2015. PNAS. 112:2900. PubMed
- Radtke?AJ,?et al.?2020.?Proc Natl Acad Sci U S A.?117:33455-65. (SB)?PubMed
- Radtke?AJ,?et al.?2022.?Nat Protoc.?17:378-401. (SB)?PubMed
- Product Citations
-
- Rosina M, et al. 2022. Cell Metab. 34:533. PubMed
- Sagnella SM, et al. 2020. Cancer Cell. 37(3):354-370. PubMed
- Zhang M, et al. 2020. Evid Based Complement Alternat Med. 8591892:2020. PubMed
- Accarias S, et al. 2020. J Cell Sci. 133:. PubMed
- Hu J, et al. 2021. Sci Adv. 7:. PubMed
- Mason HD, et al. 2021. JCI Insight. 6:e149229. PubMed
- Sepe JJ, et al. 2022. JACC Basic Transl Sci. 7:915. PubMed
- Zheng W, et al. 2021. Wellcome Open Research. 6:52. PubMed
- Zhou X, et al. 2022. Front Pharmacol. 13:887263. PubMed
- Ma C, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
- Hreha TN, et al. 2020. Front Immunol. 1.597916667. PubMed
- Glaubitz J, et al. 2022. Nat Commun. 13:4502. PubMed
- Shen H, et al. 2022. Nat Commun. 13:6030. PubMed
- Brestoff JR, et al. 2021. Cell Metab. 33:270. PubMed
- Wu T, et al. 2021. J Exp Med. :218. PubMed
- Nagai Y, et al. 2019. Front Immunol. 10:174. PubMed
- Wu Q, et al. 2022. Cell Mol Life Sci. 79:137. PubMed
- Ling X, et al. 2021. ACS Nano. 15:765. PubMed
- Peng L, et al. 2020. Transl Lung Cancer Res. 0.892361111. PubMed
- Goggi JL, et al. 2020. Mol Imaging Biol. 22:1392. PubMed
- Zheng Y, et al. 2022. Front Pharmacol. 12:816032. PubMed
- Chen D, et al. 2020. Cancer Immunol Res. 8:883. PubMed
- Al Mamun A, et al. 2019. Neurochem Int. 127:148. PubMed
- Friedman DJ, et al. 2021. Cancer Immunol Res. 9:952. PubMed
- Kennedy EM, et al. 2022. Nat Commun. 13:5907. PubMed
- Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
- Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
- Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
- Liu P, et al. 2022. iScience. 25:103867. PubMed
- Andriessen EMMA, et al. 2021. EMBO Mol Med. 13:e11754. PubMed
- Gubin MM, et al. 2018. Cell. 175:1014. PubMed
- Pizzurro GA, et al. 2021. Cancers (Basel). 13:. PubMed
- Wang G, et al. 2021. Cell Host Microbe. 29(5):777-791.e6. PubMed
- Nowak W, et al. 2020. EBioMedicine. 50:290-305.. PubMed
- Lam KC, et al. 2021. Cell. 184:5338. PubMed
- Upadhya R, et al. 2016. MBio. 7: 00547-16. PubMed
- Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
- Chhatbar C et al. 2018. Cell reports. 25(1):118-129 . PubMed
- Weinstock NI, et al. 2020. Neuron. 107(1):65-81. PubMed
- Huang T, et al. 2022. Nat Commun. 13:3489. PubMed
- Panagi M, et al. 2020. Theranostics. 10:1910. PubMed
- Heinen A, et al. 2019. Mol Ther. 27:46:00. PubMed
- Ravussin A, et al. 2018. Cell Rep. 24:1085. PubMed
- Molgora M, et al. 2020. Cell. 182:886. PubMed
- Knox T, et al. 2019. Sci Rep. 9:6136. PubMed
- Zhang L, et al. 2019. Front Immunol. 1.381944444. PubMed
- Xiao Z, et al. 2022. Mater Today Bio. 15:100297. PubMed
- Liu X, et al. 2021. Adv Sci (Weinh). 8:e2100233. PubMed
- Simoni L, et al. 2020. Cell Rep. 33:108330. PubMed
- Scholz A, et al. 2016. EMBO Mol Med. 8: 39 - 57. PubMed
- Silva HM, et al. 2019. J Exp Med. 216:786. PubMed
- Gü? E, et al. 2020. Methods Enzymol. 91:632. PubMed
- Zhu Y et al. 2017. The Journal of Neuroscience. 37(9):2362-2376 . PubMed
- Zhang SJ, et al. 2021. Adv Sci (Weinh). 8:2003410. PubMed
- RRID
- AB_2562247 (BioLegend Cat. No. 141719) AB_2562248 (BioLegend Cat. No. 141720)
- Structure
- Type I transmembrane protein, 175 kD, C-type lectin superfamily
- Distribution
-
Macrophages, dendritic cells, Langerhans cells, liver endothelial cells
- Function
- Pathogen recognition, endocytosis and phagocytosis, antigen presentation
- Ligand/Receptor
- Antigen containing mannose, fucose, or an N-acetyl glucosamine
- Cell Type
- Dendritic cells, Endothelial cells, Langerhans cells, Macrophages
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Signal Transduction
- Molecular Family
- CD Molecules
- Antigen References
-
1. Wileman TE, et al. 1986. P. Natl. Acad. Sci. USA 83:2501.
2. Apostolopoulos V, et al. 2001. Curr. Mol. Med. 1:469.
3. Burgdorf S, et al. 2006. J. Immunol. 176:6770.
4. McKenzie EJ, et al. 2007. J. Immunol. 178:4975.
- Gene ID
- 17533 View all products for this Gene ID
- UniProt
- View information about CD206 on UniProt.org
