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Purified anti-IL-34 Antibody
产品名称:
Purified anti-IL-34 Antibody
产品类别:
抗体
产品编号:
675102
产品应用:
675102
[价格]
规格 价格 库存
100µg ¥ 265 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Recombinant mouse IL-34 produced in CHO cells.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
IP - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 ?g per ml. For immunoprecipitation, the suggested use of this reagent is 2 - 5 ?g/mL. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

The theoretical MW of IL-34 is 27 kD, the observed MW is 50 kD.

RRID
AB_2565492 (BioLegend Cat. No. 675102)

Antigen Details

Structure
215 amino acids with a predicted molecular weight of approximately 26 kD.
Distribution

Expressed in different tissues including the spleen, heart, brain, lung, liver, kidney, thymus, testes, ovary, small intestine, prostrate, and colon.

Function
Regulates myeloid lineage differentiation, proliferation, and survival.
Interaction
Macrophages, monocytes, and myeloid cells.
Ligand/Receptor
CD115/M-CSF receptor (CSF-1 receptor or c-Fms)
Biology Area
Cell Biology, Immunology, Innate Immunity, Signal Transduction
Molecular Family
Cytokines/Chemokines
Antigen References

1. Lin H, et al. 2008. Sciences 320:807.
2. Chihara T, et al. 2010. Cell Death Differ. 17:1917.
3. Wei S, et al. 2010. J. Leuko. Biol. 88:495.
4. Eda H, et al. 2011. Rheumatol. 31:1525.
5. Covaleda L, et al. 2010. Virology 397:217.

Gene ID
762577 View all products for this Gene ID
UniProt
View information about IL-34 on UniProt.org

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