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Purified anti-mouse IL-22 Antibody
产品名称：
Purified anti-mouse IL-22 Antibody
产品类别：
抗体
产品编号：
517501
产品应用：
517501
[价格]
规格 价格 库存
25µg ￥ 124 1

产品详情

Product Details

Verified Reactivity
Mouse, Human
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mature recombinant protein mouse Interleukin-22 (Leu34-Val179)
Formulation
This antibody is provided in phosphate-buffered solution, pH 7.2, 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
Upon receipt, store undiluted between 2°C and 8°C.
Application

WB - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 0.5 ?g/ml dilution buffer for each mini-gel.

Application Notes

Clone BL35175 has been shown to be useful for detecting mouse and human IL-22 by Western blotting.

Product Citations
  1. Ogita T, et al. 2021. Front Nutr. 8:701466. PubMed
  2. Ke Y, et al. 2011. J Immunol. 187:2130. PubMed
  3. Jiao S, et al. 2020. Cell. 179(5):1177-1190.e13.. PubMed
RRID
AB_10695475 (BioLegend Cat. No. 517501) AB_10694243 (BioLegend Cat. No. 517502)

Antigen Details

Structure
179 aa with with a putative 33 aa signal peptide that is cleaved to generate a 147 aa mature protein.
Distribution

Secreted, Th17

Function
Cytokine that contributes to the inflammatory response in vivo.
Ligand/Receptor
Binds to IL-22 receptor complex that consists of two receptor subunits, IL22R and IL10Rβ.
Cell Type
Th17
Biology Area
Cell Biology, Signal Transduction
Molecular Family
Cytokines/Chemokines
Antigen References

1. Dumoutier L, et al. 2000. J. Immunol. 164:1814.
2. Xie MH, et al. 2000. J. Biol. Chem. 275:31335.
3. Jones BC, et al. 2008. Structure 16:1333.
4. Sonnenberg GF, et al. 2010. J. Exp. Med. 207:1293.
5. Kotenko SV, et al. 2001. J. Immunol. 166:7096.
6. Chang C, et al. 2006. Cell Research 16:902.

Gene ID
50929 View all products for this Gene ID
UniProt
View information about IL-22 on UniProt.org

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