Purified anti-human IL-17A Antibody
- 产品名称：
- Purified anti-human IL-17A Antibody
- 产品类别：
- 抗体
- 产品编号：
- 512301
- 产品应用：
- 512301
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant full length human IL-17A
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
ICFC - Quality tested
- Recommended Usage
- Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per million cells in 100 ?l volume or 100 ?l of whole blood. It isrecommended that the reagent be titrated for optimalperformance for each application.
- Product Citations
-
- Alroqi F, et al. 2017. J Clin Immunol. . 10.1007/s10875-017-0451-1. PubMed
- Matthias J, et al. 2020. J Clin Invest. 130:4587. PubMed
- Willing A, et al. 2018. J Immunol. 200:974. PubMed
- Kessel C, et al. 2017. Arthritis Rheumatol. 69:1480. PubMed
- Aravena O, et al. 2017. Arthritis Res Ther. 19:8. PubMed
- Ma F, et al. 2017. Exp Cell Res.. 10.1016/j.yexcr.2017.10.011. PubMed
- Sattler A, et al. 2021. Am J Transplant. 21:87. PubMed
- Del Alcazar D, et al. 2019. Cell Rep. 28:3047. PubMed
- Lückel C, et al. 2019. Nat Commun. 4.390277778. PubMed
- Singh AK, et al. 2017. Front Immunol. 0.513888889. PubMed
- Mishra A, et al. 2021. Cell. 184(13):3394-3409.e20. PubMed
- Schwabenland M, et al. 2021. Immunity. . PubMed
- Umeda M, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
- RRID
- AB_961398 (BioLegend Cat. No. 512301) AB_961399 (BioLegend Cat. No. 512302)
- Structure
- Cytokine; dimer; ~15 kD (Mammalian)
- Bioactivity
- Secretion of IL-6, IL-8, G-CSF, prostaglandin E2 by epithelial, endothelial or fibroblastic cells; stimulates cell migration, cord formation, and IL-6 secretion by stromal cells
- Cell Sources
- Activated T cell subpopulation
- Cell Targets
- Fibroblasts, epithelial and endothelial cells, stromal cells
- Receptors
- IL-17R
- Cell Type
- Tregs
- Biology Area
- Cell Biology, Immunology, Neuroinflammation, Neuroscience
- Molecular Family
- Cytokines/Chemokines
- Antigen References
-
1. Hirota K, et al. 2007. J. Exp. Med. 204:41.
2. Furuzawa-Carballeda J, et al. 2007. Autoimmun. Rev. 6:169.
3. Witowski J, et al. 2007. Kidney Int. 71:514.
4. Gaffen SL, et al. 2006. Vitam. Horm. 74:255.
5. Hymowitz S, et al. 2001. EMBO J. 20:5332.
- Gene ID
- 3605 View all products for this Gene ID
- UniProt
- View information about IL-17A on UniProt.org
