PerCP/Cyanine5.5 anti-human IL-17A Antibody
- 产品名称：
- PerCP/Cyanine5.5 anti-human IL-17A Antibody
- 产品类别：
- 抗体
- 产品编号：
- 512313
- 产品应用：
- 512313
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant full length human IL-17A
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PerCP/Cyanine5.5 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The IL-17A antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICFC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells or 20 ?l per 100 ?l of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.
- Additional Product Notes
- BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.
- Product Citations
-
- Lu T, et al. 2016. PLoS One. 11: 0148044. PubMed
- Al-Daghri N, et al. 2012. J Immunol. 188:1325. PubMed
- Antonelli L, et al. 2010. Blood. 116:3818. PubMed
- Yang R, et al. 2020. Cell. 183(7):1826-1847.e31. PubMed
- Hilchey S, et al. 2011. Blood. 118:3591. PubMed
- Peelen E, et al. 2013. J Neuroimmunol. 258:77. PubMed
- Smolders J, et al. 2010. PLoS One. 5:e15235. PubMed
- Dai G, et al. 2021. JCI Insight. 6:. PubMed
- Ferry GM, et al. 2022. Front Immunol. 13:863155. PubMed
- Qi Y, et al. 2012. PLoS One. 7:e39072. PubMed
- Tian T, et al. 2015. PLoS One. 10: 0131761. PubMed
- Paris R, et al. 2015. PLoS One. 10: 0144767. PubMed
- RRID
- AB_961397 (BioLegend Cat. No. 512313) AB_961396 (BioLegend Cat. No. 512314)
- Structure
- Cytokine; dimer; ~15 kD (Mammalian)
- Bioactivity
- Secretion of IL-6, IL-8, G-CSF, prostaglandin E2 by epithelial, endothelial or fibroblastic cells; stimulates cell migration, cord formation, and IL-6 secretion by stromal cells
- Cell Sources
- Activated T cell subpopulation
- Cell Targets
- Fibroblasts, epithelial and endothelial cells, stromal cells
- Receptors
- IL-17R
- Cell Type
- Tregs
- Biology Area
- Cell Biology, Immunology, Neuroinflammation, Neuroscience
- Molecular Family
- Cytokines/Chemokines
- Antigen References
-
1. Hirota K, et al. 2007. J. Exp. Med. 204:41.
2. Furuzawa-Carballeda J, et al. 2007. Autoimmun. Rev. 6:169.
3. Witowski J, et al. 2007. Kidney Int. 71:514.
4. Gaffen SL, et al. 2006. Vitam. Horm. 74:255.
5. Hymowitz S, et al. 2001. EMBO J. 20:5332.
- Gene ID
- 3605 View all products for this Gene ID
- UniProt
- View information about IL-17A on UniProt.org
