Brilliant Violet 421™ anti-human IL-17A Anti
- 产品名称：
- Brilliant Violet 421™ anti-human IL-17A Anti
- 产品类别：
- 抗体
- 产品编号：
- 512321
- 产品应用：
- 512321
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant full length human IL-17A
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421? under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICFC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
Brilliant Violet 421? excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421? is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet?.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
- Violet Laser (405 nm)
- Additional Product Notes
View more applications data for this product in our Scientific Poster Library.
- Product Citations
-
- Barros-Martins J, et al. 2021. Nat Med. 27:1525. PubMed
- Leeansyah E, et al. 2015. PLoS Pathog. 11: 1005072. PubMed
- Zuazo M, et al. 2019. EMBO Mol Med. 11(7). PubMed
- Booth JS, et al. 2019. Hum Vaccin Immunother. :1. PubMed
- Nicholas DA et al. 2019. Cell Metab. 30(3):447-461 . PubMed
- Torres-Ruiz J, et al. 2021. Front Immunol. 12:689966. PubMed
- Bailur JK, et al. 2020. JCI Insight. 5:00. PubMed
- Wood MP, et al. 2020. J Infect Dis. 222:44. PubMed
- Shen X, et al. 2021. Front Immunol. 12:710750. PubMed
- Ohue Y, et al. 2014. Clin Cancer Res. 20:5052. PubMed
- Faust HJ, et al. 2020. J Clin Invest. 130:5493. PubMed
- Anderson AE, et al. 2022. NPJ Regen Med. 7:6. PubMed
- Khaitan A, et al. 2016. PLoS One. 11: 0161786. PubMed
- Khuzwayo S, et al. 2021. Front Immunol. 12:631410. PubMed
- Hackstein CP, et al. 2022. Nat Commun. 13:7472. PubMed
- RRID
- AB_10899566 (BioLegend Cat. No. 512321) AB_11218604 (BioLegend Cat. No. 512322)
- Structure
- Cytokine; dimer; ~15 kD (Mammalian)
- Bioactivity
- Secretion of IL-6, IL-8, G-CSF, prostaglandin E2 by epithelial, endothelial or fibroblastic cells; stimulates cell migration, cord formation, and IL-6 secretion by stromal cells
- Cell Sources
- Activated T cell subpopulation
- Cell Targets
- Fibroblasts, epithelial and endothelial cells, stromal cells
- Receptors
- IL-17R
- Cell Type
- Tregs
- Biology Area
- Cell Biology, Immunology, Neuroinflammation, Neuroscience
- Molecular Family
- Cytokines/Chemokines
- Antigen References
-
1. Hirota K, et al. 2007. J. Exp. Med. 204:41.
2. Furuzawa-Carballeda J, et al. 2007. Autoimmun. Rev. 6:169.
3. Witowski J, et al. 2007. Kidney Int. 71:514.
4. Gaffen SL, et al. 2006. Vitam. Horm. 74:255.
5. Hymowitz S, et al. 2001. EMBO J. 20:5332.
- Gene ID
- 3605 View all products for this Gene ID
- UniProt
- View information about IL-17A on UniProt.org
