Alexa Fluor® 647 anti-human IL-17A Antibody
- 产品名称：
- Alexa Fluor® 647 anti-human IL-17A Antibody
- 产品类别：
- 抗体
- 产品编号：
- 512309
- 产品应用：
- 512309
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant full length human IL-17A
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 647 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The IL-17A antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICFC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor? 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
- Red Laser (633 nm)
- Product Citations
-
- Chuang H, et al. 2014. Nat Commun. 5:4602. PubMed
- Sanchez-Vargas LA, et al. 2020. Viruses. 12:. PubMed
- Meng KP, et al. 2020. J Exp Med. 217:00:00. PubMed
- Konermann A, et al. 2012. Cell Immunol. 272:137. PubMed
- Doherty G, et al. 2012. Eur J Immunol. 42:3062. PubMed
- Jardine L, et al. 2019. Nat Commun. 10:1999. PubMed
- Nguyen X, Ehrenstein M 2016. J Exp Med. 213: 1241 - 1253. PubMed
- Conti L, et al. 2014. J Immunol. 188:1011. . PubMed
- McGowan J, et al. 2019. Front Immunol. 10:1553. PubMed
- RRID
- AB_961389 (BioLegend Cat. No. 512309) AB_961388 (BioLegend Cat. No. 512310)
- Structure
- Cytokine; dimer; ~15 kD (Mammalian)
- Bioactivity
- Secretion of IL-6, IL-8, G-CSF, prostaglandin E2 by epithelial, endothelial or fibroblastic cells; stimulates cell migration, cord formation, and IL-6 secretion by stromal cells
- Cell Sources
- Activated T cell subpopulation
- Cell Targets
- Fibroblasts, epithelial and endothelial cells, stromal cells
- Receptors
- IL-17R
- Cell Type
- Tregs
- Biology Area
- Cell Biology, Immunology, Neuroinflammation, Neuroscience
- Molecular Family
- Cytokines/Chemokines
- Antigen References
-
1. Hirota K, et al. 2007. J. Exp. Med. 204:41.
2. Furuzawa-Carballeda J, et al. 2007. Autoimmun. Rev. 6:169.
3. Witowski J, et al. 2007. Kidney Int. 71:514.
4. Gaffen SL, et al. 2006. Vitam. Horm. 74:255.
5. Hymowitz S, et al. 2001. EMBO J. 20:5332.
- Gene ID
- 3605 View all products for this Gene ID
- UniProt
- View information about IL-17A on UniProt.org
