Alexa Fluor® 488 anti-human IL-17A Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 165	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Recombinant full length human IL-17A

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 488 under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

* Alexa Fluor? 488 has a maximum emission of 519 nm when it is excited at 488 nm.

Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

View full statement regarding label licenses

Excitation Laser

Blue Laser (488 nm)

Product Citations

Corral-Jara KF, et al. 2021. Mol Biomed. 2:9. PubMed
Canavan M, et al. 2018. JCI Insight. 3:. PubMed
Meng S, et al. 2018. Mol Med Rep. 18:4247. PubMed
Linehan JL et al. 2018. Cell. 172(4):784-796 . PubMed
Grandclaudon M, et al. 2019. Cell. 179:432. PubMed
Rauen T, et al. 2012. Genes Immun. 0.781944444. PubMed
Hirota K et al. 2018. Immunity. 48(6):1220-1232 . PubMed

RRID

AB_961387 (BioLegend Cat. No. 512307) AB_961386 (BioLegend Cat. No. 512308)

Antigen Details

Structure: Cytokine; dimer; ~15 kD (Mammalian)
Bioactivity: Secretion of IL-6, IL-8, G-CSF, prostaglandin E2 by epithelial, endothelial or fibroblastic cells; stimulates cell migration, cord formation, and IL-6 secretion by stromal cells
Cell Sources: Activated T cell subpopulation
Cell Targets: Fibroblasts, epithelial and endothelial cells, stromal cells
Receptors: IL-17R
Cell Type: Tregs
Biology Area: Cell Biology, Immunology, Neuroinflammation, Neuroscience
Molecular Family: Cytokines/Chemokines
Antigen References: 1. Hirota K, et al. 2007. J. Exp. Med. 204:41.
2. Furuzawa-Carballeda J, et al. 2007. Autoimmun. Rev. 6:169.
3. Witowski J, et al. 2007. Kidney Int. 71:514.
4. Gaffen SL, et al. 2006. Vitam. Horm. 74:255.
5. Hymowitz S, et al. 2001. EMBO J. 20:5332.
Gene ID: 3605 View all products for this Gene ID
UniProt: View information about IL-17A on UniProt.org

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