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Biotin anti-human IL-15 Antibody
产品名称:
Biotin anti-human IL-15 Antibody
产品类别:
抗体
产品编号:
515103
产品应用:
515103
[价格]
规格 价格 库存
50µg ¥ 124 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
E. coli - expressed, recombinant human IL-15
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application

ELISA Detection - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by ELISA assay. For use as an ELISA detection antibody, a concentration range of 0.5-2.0 ?g/ml is recommended. To obtain a linear standard curve, serial dilutions of IL-15 recombinant protein ranging from 500 to 7.8 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

The biotinylated BH1543 antibody is useful as a detection antibody for a sandwich ELISA assay, when used in conjunction with purified BH1509 (Cat. No. 515002) antibody as the capture antibody and recombinant human IL-15 (Cat. No. 570309) as the standard.

RRID
AB_2561320 (BioLegend Cat. No. 515103) AB_2561321 (BioLegend Cat. No. 515104)

Antigen Details

Structure
13 kD single non-glycosylated polypeptide
Distribution
T cells, B cells, dendritic cells, monocytes, and macrophages
Function
IL-15 stimulates the proliferation of activated T cells, NK cells, and B cells, inducing immunoglobulin synthesis by B cells stimulated by anti-IgM or CD40 ligand. In addition, IL-15 promotes the development of dendritic cells, activates human neutrophils, and induces the production of proinflammatory cytokines from macrophages.
Interaction
T lymphocytes, NK cells
Ligand/Receptor
IL-15Rα, IL-15Rβ and IL-15γc
Cell Type
T cells, B cells, Dendritic cells, Monocytes, Macrophages
Biology Area
Immunology, Innate Immunity
Molecular Family
Cytokines/Chemokines
Antigen References

1. Grabstein K,?et al.?1994.?Science?264:965.
2. Ma A,?et al.?2006.?Annu. Rev. Immunol.?24:657.
3. Meresse B,?et al.?2004.?Immunity?21:357.
4. Armitage RJ,?et al.?1995.?J. Immunol.?154:483.
5. Pulendran B,?et al.?2004.?Eur. J. Immunol.?34:66.
6. Bouchard A,?et al.?2004.?J. Leuko. Biol.?75:893.
7. Ratthe C,?et al.?2004.?J. Leuko. Biol.?76:162.
8. Feng T,?et al.?2008.?Cell Immunol.?5:189.
9. Rubinstein MP,?et al.?2006.?P. Natl. Acad. Sci. USA?103:9166.

Gene ID
3600 View all products for this Gene ID
UniProt
View information about IL-15 on UniProt.org

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