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PerCP anti-human IL-8 Antibody
产品名称:
PerCP anti-human IL-8 Antibody
产品类别:
抗体
产品编号:
514606
产品应用:
514606
[价格]
规格 价格 库存
100tests ¥ 288 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant human IL-8, amino acids Ser28-Ser99 (Accession # NM_000584)
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PerCP under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

* PerCP has a maximum absorption of 482 nm and a maximum emission of 675 nm.

Excitation Laser
Blue Laser (488 nm)
Application Notes

ELISA Capture: The purified BH0814 antibody is useful as the capture antibody in a sandwich ELISA assay, when used in conjunction with the biotinylated BH0840 (Cat. No. 514703/ 514704) antibody as the detecting antibody and recombinant human IL-8 (Cat. # 570909) as the standard.

Product Citations
  1. Santos R, et al. 2017. Stem Cell Reports. 1.553472222. PubMed
RRID
AB_10639867 (BioLegend Cat. No. 514606)

Antigen Details

Structure
CXC chemokine; 8.4 kD (Mammalian)
Ligand/Receptor
CXCR1 (CDw128); CXCR2
Bioactivity
Neutrophil/basophil chemoattractant; activates neutrophils, angiogenic factor
Cell Sources
Monocytes, lymphocytes, granulocytes, fibroblasts, endothelial cells, bronchial epithelial cells, keratinocytes, melanocytes, hepatocytes, mesangial cells, chondrocytes
Cell Targets
Neutrophils, basophils, lymphocytes
Receptors
CXCR1 (CDw128); CXCR2
Cell Type
Neutrophils
Biology Area
Cell Biology, Immunology, Neuroinflammation, Neuroscience
Molecular Family
Cytokines/Chemokines
Antigen References

1. Fitzgerald K, et al. Eds. 2001. The Cytokine FactsBook. Academic Press San Diego.
2. Baggiolini M, et al. 1994. Adv. Immunol. 55:97.
3. Schr?der J, et al. 1992. Immunology Ser. 57:387.
4. Zwahlen R, et al. 1993. Intl. Rev. Expt. Pathol. 34:27.

Regulation
Upregulated by IL-1, IL-7, IL-17, IFN-γ, TNF-α, leukoregulin; downregulated by IL-4, TGF-β, glucocorticoids, vitamin D3
Gene ID
3576 View all products for this Gene ID
UniProt
View information about IL-8 on UniProt.org

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