Biotin anti-mouse IL-27 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
50µg	￥ 147	1

Product Details

Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Recombinant mouse IL-27
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application: ELISA Detection - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by?ELISA assay. A concentration of 0.125 ?g/ml of the capture antibody was utilized to generate the example standard curve. It is recommended that the end-user titrate each lot of reagents for optimal performance.
Application Notes: ELISA Detection:?To measure mouse IL-27, this antibody can be used as a detection antibody in sandwich ELISA format and paired with the purified MM27-7B1?antibody (Cat. No. 516902) as the capture antibody. Recombinant Mouse IL-27 (ELISA Std.) (Cat. No.?577409) can be used as the protein standard.
Note:?For measuring mouse IL-27 in serum, plasma or cell culture supernatant,?LEGEND MAX? Mouse IL-27 Heterodimer ELISA Kit?with Pre-coated Plates (Cat. No.?438707?&?438708) are specially developed and recommended.
RRID: AB_2563423 (BioLegend Cat. No. 525903) AB_2563424 (BioLegend Cat. No. 525904)

Structure: A heterodimeric cytokine consisting of EBV-induced gene-3 (EBI3, an IL-12 p40-related protein) and p28 (a newly discovered IL-12 p35-related protein).
Distribution: Produced by antigen-presenting cells, including macrophages and dendritic cells.
Function: Drives rapid clonal expansion of na?ve CD4⁺ T cells, promotes Th1 polarization and IFN-?? production; plays a role in the anti-inflammatory and antitumor reponses, and has potential in autoimmune disease therapy.
Interaction: T cells and NK cells.
Ligand/Receptor: IL-27R (TCCR) (WSX-1).
Cell Type: Antigen-presenting cells, Macrophages, Dendritic cells, B cells
Biology Area: Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Immunology, Signal Transduction
Molecular Family: Cytokines/Chemokines
Antigen References: 1. Salcedo R, et al. 2004. J. Immunol. 173:7170.
2. Owaki T, et al. 2005. J. Immunol. 175:2191.
3. Pflanz S, et al. 2002. Immunity 16:779.
4. Diveu C, et al. 2009. J. Immunol. 182:5748.
5. Morishima N, et al. 2005. J. Immunol. 175:1686.
6. Liu J, et al. 2007. J. Exp. Med. 204:141.
Gene ID: 246779 View all products for this Gene ID
UniProt: View information about IL-27 on UniProt.org