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Purified anti-SARS-CoV-2 S Protein S1 Antibody
产品名称:
Purified anti-SARS-CoV-2 S Protein S1 Antibody
产品类别:
抗体
产品编号:
945101
产品应用:
945101
[价格]
规格 价格 库存
25µg ¥ 112 1

产品详情

Product Details

Verified Reactivity
SARS-CoV-2
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Partial recombinant SARS-CoV-2 S protein corresponding to S1 subunit
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
Direct ELISA, FC - Verified

Recommended Usage

Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 1.0 ?g/mL. For?Direct ELISA, a concentration of 114.9 ng/mL is recommended. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5??g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

BioLegend offers multiple clones that recognize SARS-CoV-2 S protein S1. Clone A20103H displayed the strongest performance for western blot of all clones validated for the application.

Product Citations
  1. Mamedov T, et al. 2021. Viruses. 13:. PubMed
RRID
AB_2890875 (BioLegend Cat. No. 945101) AB_2890875 (BioLegend Cat. No. 945102)

Antigen Details

Structure
Spike glycoprotein is a homotrimer. Each monomer consists of 1,273 amino acids with a theoretical molecular weight of 141 kD, and consists of S1 and S2 subunits.
Distribution

Viral envelope protein, host cell membrane, host cell endoplasmic reticulum-Golgi intermediate compartment membrane?

Function
Mediates fusion between virus and host cell membranes
Interaction
ACE2
Ligand/Receptor
ACE2
Biology Area
COVID-19
Antigen References

1. Walls AC, et al. 2020. Cell. 181(2):281-292.
2. Yan R, et al. 2020. Science. 367 (6485):1444-1448.
3. Wrapp D, et al. 2020. Science. 367 (6483):1260-1263.
4. Shang J, et al. 2020. PNAS. 117(21):11727-11734

Gene ID
43740568 View all products for this Gene ID
UniProt
View information about Viral Protein on UniProt.org

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