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Ultra-LEAF™ Purified anti-mouse CXCL5 (LIX)
产品名称:
Ultra-LEAF™ Purified anti-mouse CXCL5 (LIX)
产品类别:
抗体
产品编号:
662053
产品应用:
662053
[价格]
规格 价格 库存
100µg ¥ 358 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Recombinant mouse CXCL5 (LIX)
Formulation
0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is < 0.01 EU/?g of the protein (< 0.001 ng/?g of the protein) as determined by the LAL test.
Preparation
The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Concentration
The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
Application

Neut - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by neutralizing the chemotaxis induced by recombinant mouse CXCL5 (LIX) (Cat. No. 573302) at 0.8 ng/mL on mouse Baf3- mCXCR2 transfectant chemoattractant cells. ND50 range: 0.025 - 0.25 ?g/mL. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2910492 (BioLegend Cat. No. 662053) AB_2910492 (BioLegend Cat. No. 662054)

Antigen Details

Structure
Chemokine
Distribution

Endothelial cells, fibroblasts, monocytes, macrophages, platelets, alveolar type II cells

Function
CXCL5 chemoattracts and activates neutrophils during inflammation, and it is induced by LPS and inflammatory cytokines. NH2-terminal truncation enhances, whereas citrullination decreases the chemotactic properties of CXCL5.
Interaction
Neutrophils
Ligand/Receptor
CXCR2
Antigen References
  1. Wuyts A, et al. 1999. J?Immunol. 163:6155-63.
  2. Jeyaseelan S, et al. 2005. Am?J?Respir?Cell?Mol?Biol. 32:531-9.
  3. Mei J, et al. 2010. Immunity. 33:106-17.
  4. Montier A, et al. 2010. J Biol?Chem. 285:29750-9.
  5. Grommes J and Soehnlein O. 2011. Mol?Med. 17:293-307.
Gene ID
20304 View all products for this Gene ID
UniProt
View information about CXCL5 on UniProt.org

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