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Purified anti-ATP1A1 Antibody
产品名称:
Purified anti-ATP1A1 Antibody
产品类别:
抗体
产品编号:
604751
产品应用:
604751
[价格]
规格 价格 库存
25µg ¥ 110 1

产品详情

Product Details

Verified Reactivity
Human, Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Synthetic peptide conjugated to KLH
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
IHC-P, ICC - Verified?

Recommended Usage

Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.125 - 0.5??g/mL.?For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 1.0 - 10.0??g/mL is suggested.?For immunocytochemistry, a concentration range of 2.5 - 5.0?μg/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

For ICC, we recommend 4% PFA fixation followed by permeabilization with ice cold methanol, or fixation/permeabilization with ice cold methanol alone. We do not recommend 4% PFA fixation followed by permeabilization with 0.5% Triton-X.

RRID
AB_2924609 (BioLegend Cat. No. 604751) AB_2924609 (BioLegend Cat. No. 604752)

Antigen Details

Structure
ATP1A1 can be processed by alternative splicing into 4 different isoforms; isoform 1 is a 1023 aa protein with a predicted molecular weight of 113kD.
Distribution

ATP1A1 is widely expressed in the plasma membrane of most tissues.

Function
ATP1A1 is an ATPase involved in maintaining the balance of Na+ and K+ across of the plasma membrane.
Biology Area
Cell Biology, COVID-19
Molecular Family
Enzymes and Regulators, Ion Channels
Antigen References
  1. Takase S, et al.?2017.?Sci Rep.?7:2002.
  2. Wu IC, et al. Oncotarget. 2016 Dec 20;7(51):85244-85258
  3. Schlingmann KP, et al.?2018.?Am J Hum Genet.?103:808-816.
  4. Zacherl S, et al.?2015.?J Biol Chem.?290:3654-65.
  5. Azizan EA, et al.?2013.?Nat Genet.?45:1055-60.
Gene ID
476 View all products for this Gene ID
UniProt
View information about ATP1A1 on UniProt.org

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