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Purified anti-BLNK Phospho (Tyr96) Antibody
产品名称:
Purified anti-BLNK Phospho (Tyr96) Antibody
产品类别:
抗体
产品编号:
608351
产品应用:
608351
[价格]
规格 价格 库存
25µg ¥ 134 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Synthetic peptide corresponding to human BLNK phosphorylated at Tyrosine 96
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
ICC, ICFC - Verified

Recommended Usage

Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.1 ?g/mL.?For immunocytochemistry, a concentration range of 1.25 - 5.0 μg/mL is recommended.?For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This product has high background in WB if used at concentrations above 0.2 μg/mL.

This product is not suitable for ICC if cells are fixed with methanol only.

Antigen Details

Structure
BLNK is a 456 amino-acid protein with a predicted molecular weight of 50 kD.
Distribution

BLNK is expressed in cytoplasm of B cells.

Function
Activation of BLNK plays a critical role in B cell proliferation, differentiation, and apoptosis.
Interaction
BLNK interacts with Grb2, Vav, PLCγ2, and Nck1.
Cell Type
B cells
Biology Area
Cell Biology
Molecular Family
Adaptor Proteins, Phospho-Proteins
Antigen References
  1. Fu C, et al. 1998. Immunity. 9:93-103.
  2. Kurosaki T & Tsukada S. 2000. Immunity. 12:1-5.
  3. Gauld SB, et al. 2002. Science. 296:1641-2.
  4. Minegishi Y, et al. 1999. Science. 286:1954-7.
Gene ID
29760 View all products for this Gene ID
UniProt
View information about BLNK Phospho Tyr96 on UniProt.org

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