Ultra-LEAF™ Purified anti-mouse CD155 (PVR) -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 358	1

Product Details

Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Recombinant mouse CD155
Formulation: 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is < 0.01 EU/?g of the protein (< 0.001 ng/?g of the protein) as determined by the LAL test.
Preparation: The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Concentration: The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
Application: Blocking - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by blocking the binding of 0.2 ?g/mL biotinylated recombinant mouse TIGIT to 1 ?g/mL immobilized recombinant mouse CD155-Fc chimera. ND₅₀ = 0.05 – 0.25 ?g/mL. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2890862 (BioLegend Cat. No. 942103) AB_2890862 (BioLegend Cat. No. 942104)

Structure: Disulfide-linked homodimer
Distribution: Highly expressed on immature thymocytes, lymph node dendritic cells, and tumor cells of epithelial and neuronal origin, preferentially expressed on Th17 cells.
Function: Mediates NK cell adhesion and triggers NK cell effector functions
Interaction: NK cell, T cell
Ligand/Receptor: Vitronectin, nectin-3, DNAM-1/CD226, CD96, and TIGIT
Cell Type: Dendritic cells, Th17, Thymocytes
Biology Area: Adaptive Immunity, Cell Adhesion, Cell Motility/Cytoskeleton/Structure, Neuroscience
Molecular Family: Adhesion Molecules, Soluble Receptors
Antigen References: 1. He Y, et al. 2000. Proc. Natl. Acad. Sci. USA. 97:79-84.?
2. Bottino C, et al. 2003. J. Exp. Med. 198:557-67.?
3. Fuchs A, et al. 2004. J. Immun. 172: 3994-3998.?
4. Reymond N, et al. 2004. J. Exp. Med. 199:1331-41.?
5. Koike S, et al. 1990. EMBO J. 9: 3217-3224.?
6. Mendelsohn CL, et al. 1989. Cell 56:855-65.
Gene ID: 52118 View all products for this Gene ID
UniProt: View information about CD155 on UniProt.org