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首页 > 抗体蛋白 > 抗体
Purified anti-Optineurin Antibody
产品名称：
Purified anti-Optineurin Antibody
产品类别：
抗体
产品编号：
870101
产品应用：
870101
[价格]
规格 价格 库存
25µg ￥ 106 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant human optineurin protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB -?Quality tested
ICC -?Verified
Recommended Usage

Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 2.0?- 10??g/mL. For immunocytochemistry, a concentration range of 2.0?- 10?μg/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2820186 (BioLegend Cat. No. 870101) AB_2820187 (BioLegend Cat. No. 870102)

Antigen Details

Structure
Human optineurin is a 577 amino acid protein with a predicted molecular mass of 66 kD and an observed molecular mass of 74 kD.
Distribution

Tissue distribution: Widely expressed in tissues

Cellular distribution: Nucleus, endosome, cytosol, Golgi apparatus, mitochondrion, lysosome

Function
Optineurin plays an important role in the maintenance of the Golgi complex, membrane trafficking and exocytosis.
Interaction
Interacts with myosin VI and Rab8
Cell Type
Astrocytes, Neurons
Biology Area
Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation, Protein Trafficking and Clearance
Molecular Family
Adaptor Proteins
Antigen References
  1. Osawa T, et al. 2011. Neuropathology. 31:569-74.
  2. Ying H, Yue BY. 2012. Int. Rev. Cell. Mol. Biol. 294: 223-58.?
  3. Korac J, et al. 2013. J. Cell. Sci. 126: 580-92.
Gene ID
10133 View all products for this Gene ID
UniProt
View information about Optineurin on UniProt.org

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