PE anti-human CD366 (Tim-3) Antibody
- 产品名称：
- PE anti-human CD366 (Tim-3) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 364805
- 产品应用：
- 364805
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human Tim-3
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- RRID
- AB_2922577 (BioLegend Cat. No. 364805) AB_2922577 (BioLegend Cat. No. 364806)
- Structure
- Transmembrane protein containing immunoglobulin domain and mucin-like domain; can exist as a soluble form lacking mucin and transmembrane domains
- Distribution
-
Activated T cells, preferentially on Th1 cells, monocytes, dendritic cells
- Function
- CD366 plays a role in regulating macrophage activation, checkpoint inhibitor, T cell apoptosis and immune tolerance
- Ligand/Receptor
- Galectin-9 and PtdSer
- Molecular Family
- CD Molecules, Immune Checkpoint Receptors
- Antigen References
-
- Hafler DA and Kuchroo V. 2008. J?Exp?Med.?205:2699.
- Zhu C, et al. 2005. Nat?Immunol. 6:1245.
- Wang F, et al. 2009. Immunobiology.?214:342.
- Gene ID
- 84868 View all products for this Gene ID
- UniProt
- View information about CD366 on UniProt.org
