Biotin anti-Rab8 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 129	1

Product Details

Verified Reactivity: Human, Mouse, Rat
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Recombinant human Rab8A
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application: ICC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunocytochemistry. For immunocytochemistry, a concentration range of 0.2 - 5.0 μg/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: This clone cross-react with Rab8A and Rab8B.
RRID: AB_2820158 (BioLegend Cat. No. 865403) AB_2820159 (BioLegend Cat. No. 865404)

Antigen Details

Structure

Rab8 is a 207 amino acid protein with an apparent molecular mass of ~24 kD.

Distribution

Tissue Distribution: ubiquitously expressed
Cellular Distribution: Plasma membrane, cytoskeleton, cytosol, Golgi Apparatus, and endosome.

Function

Rab8 is a GTPase that plays an important role in intracellular membrane trafficking.

Interaction

MICALL1, MICALL2, Optineurin, MAP4K2

Cell Type

Astrocytes, Dopaminergic Neurons, GABAergic Neurons, Glutamatergic Neurons, Mature Neurons, Microglia, Neural Stem Cells, Neurons, Oligodendrocytes

Biology Area

Cancer Biomarkers, Cell Biology, Cell Cycle/DNA Replication, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation, Protein Trafficking and Clearance, Synaptic Biology

Molecular Family

Autophagosome Markers, Cytoskeletal Proteins, Organelle Markers, Tumor Suppressors

Antigen References