Purified anti-Cofilin 1 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 106	1

Product Details

Verified Reactivity: Human, Mouse, Rat
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Human CFL1 recombinant protein (a.a. Met 1 - Leu 166)
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
IHC-P, ICC - Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 2.0 - 10 ?g per mL. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 1.0 - 5.0 ?g/mL is suggested.?For immunocytochemistry, a concentration range of 2.0 - 10 μg/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: For WB on brain lysates, 5 - 10 ?g/mL is recommended.
RRID: AB_2810771 (BioLegend Cat. No. 865301) AB_2810772 (BioLegend Cat. No. 865302)

Antigen Details

Structure

Cofilin 1 is a 166 amino acid protein with an apparent molecular mass of ~19 kD.

Distribution

Tissue Distribution: Immune system, gastrointestinal tract, lung, testis, and skin
Cellular Distribution: Nucleus, cytosol, plasma membrane, cytoskeleton, and mitochondrion

Interaction

Cofilin 1 plays a role in cytoskeleton dynamics by regulating F-actin depolimerization

Ligand/Receptor

HSPH1, LIMK1, F-actin

Cell Type

Astrocytes, Dopaminergic Neurons, GABAergic Neurons, Glutamatergic Neurons, Mature Neurons, Microglia, Neural Stem Cells, Neurons, Oligodendrocytes

Biology Area

Cancer Biomarkers, Cell Biology, Cell Motility/Cytoskeleton/Structure, Cell Proliferation and Viability, Cell Structure, Neurodegeneration, Neuroscience, Synaptic Biology

Molecular Family

Cytoskeletal Proteins, GTPases, Scaffold Proteins

Antigen References