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Purified anti-Ataxin-2 Antibody
产品名称:
Purified anti-Ataxin-2 Antibody
产品类别:
抗体
产品编号:
868001
产品应用:
868001
[价格]
规格 价格 库存
25µg ¥ 106 1

产品详情

Product Details

Verified Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human ataxin-2 recombinant protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
IHC-P - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1 - 10 ?g per ml. For formalin-fixed paraffin-embedded immunohistochemical staining, a concentration range of 1 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2810809 (BioLegend Cat. No. 868001) AB_2810810 (BioLegend Cat. No. 868002)

Antigen Details

Structure
Human ataxin-2 is a 1,313 amino acid protein with a predicted molecular mass of 140 kD.
Distribution

Tissue distribution: Brain, spinal cord, heart, liver, skeletal muscle, pancreas, and placenta
Cellular distribution: Cytoplasm

Function
Ataxin-2 is involved in the RNA splicing, protein interactions, and metabolic homeostasis.
Interaction
Ataxin-2 interacts with TARDBP, RBFOX1, polyribosomes, SH3GL2, SH3GL3, SH3KBP1, CBL, EGFR, and ATXN2L.
Cell Type
Neurons
Biology Area
Neurodegeneration, Neuroscience, Synaptic Biology
Antigen References

Carmo-Silva?S, et al. 2017. Trends Endocrinol Metab. 28(4):309-318.
van den Heuvel DM, et al. 2014. Trends Mol Med.?20(1):25-35.
Becker LA, et al. 2017. Nature. 544(7650):367-371.
Scoles DR, et al. 2017. Nature. 544(7650):362-366

Gene ID
6311 View all products for this Gene ID
UniProt
View information about Ataxin-2 on UniProt.org

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