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Purified anti-human CD279 (PD-1) Antibody
产品名称:
Purified anti-human CD279 (PD-1) Antibody
产品类别:
抗体
产品编号:
621602
产品应用:
621602
[价格]
规格 价格 库存
100µg ¥ 89 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant human CD279 protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5??g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

A17188B antibody can block the binding of NAT105 and EH12.2H7 antibodies to the target.

Product Citations
  1. Le X, et al. 2021. J Thorac Oncol. 16:583. PubMed
RRID
AB_2820103 (BioLegend Cat. No. 621602)

Antigen Details

Structure
55 kD type I transmembrane protein
Distribution

Transiently expressed on CD4- and CD8- thymocytes, upregulated in thymocytes and splenic T and B lymphocytes, and is expressed on activated myeloid cells.

Function
Signaling and co-stimulation (co-inhibition)
Interaction
SHP-1 and SHP-2
Ligand/Receptor
PD-L1 (CD274) and PD-L2 (CD273)
Cell Type
Lymphocytes, T cells
Biology Area
Cell Biology, Immuno-Oncology, Inhibitory Molecules
Molecular Family
CD Molecules
Antigen References
  1. Ishida Y, et al. 1992. EMBO J. 11:3887
  2. Francisco LM, et al. 2010. Immunol Rev. 236:219
Gene ID
5133 View all products for this Gene ID
UniProt
View information about CD279 on UniProt.org

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