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Alexa Fluor® 594 anti-α-Synuclein, aggre
产品名称:
Alexa Fluor® 594 anti-α-Synuclein, aggre
产品类别:
抗体
产品编号:
864907
产品应用:
864907
[价格]
规格 价格 库存
25µg ¥ 136 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Recombinant human alpha-synuclein aggregates
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 594 under optimal conditions.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

IHC-P - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 0.5 - 10??g/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor? 594 has an excitation maximum of 590 nm, and a maximum emission of 617 nm.


Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

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RRID
AB_2861089 (BioLegend Cat. No. 864907) AB_2861090 (BioLegend Cat. No. 864908)

Antigen Details

Structure
Human α-synuclein is a 140 amino acid protein with a molecular mass of 14 kD.
Distribution

Tissue distribution: Primarily nervous system, but lower expression in other tissues such as blood and skin.

Cellular distribution: Cytoskeleton, cytosol, lysosome, mitochondria, nucleus, plasma membrane, and extracellular.

Function
α-synuclein plays several roles in synaptic activity such as synaptic vesicle trafficking and neurotransmitter release. It is also involved in the regulation of gene expression.
Interaction
Interacts with various proteins, such as UCHL1, phospholipase D,histones and SNARE components.
Cell Type
Neurons
Biology Area
Cell Biology, Mitochondrial Function, Neurodegeneration, Neuroinflammation, Neuroscience, Protein Misfolding and Aggregation, Protein Trafficking and Clearance, Synaptic Biology
Molecular Family
α-Synuclein, Presynaptic proteins, Synaptic Vesicle Trafficking/Endocytosis
Gene ID
6622 View all products for this Gene ID
UniProt
View information about alpha-Synuclein on UniProt.org

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