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HRP anti-RAGE Antibody
产品名称：
HRP anti-RAGE Antibody
产品类别：
抗体
产品编号：
855903
产品应用：
855903
[价格]
规格 价格 库存
25µg ￥ 132 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant Human RAGE
Formulation
This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
Preparation
The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Application

WB - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.05 - 1.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2801211 (BioLegend Cat. No. 855903) AB_2801212 (BioLegend Cat. No. 855904)

Antigen Details

Structure
RAGE is a 404 amino acid protein with an apparent molecular mass of ~43 kD.
Distribution

Tissue Distribution: Lung (major) and colon (less expressed)

Cellular Distribution: Plasma membrane, extracellular, and nucleus

Function
Functions as a pattern recognition receptor in the innate immune system that initiates proinflammatory responses.
Interaction
RAGE forms homo-dimers, and interacts with HMGB1, S100A1, APP, S100B, S100A12, and S100A14.
Ligand/Receptor
AGEs (advanced glycation end-products)
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Antigen References
  1. Barbezier N, et al. 2014. Ann. Biol. Clin. (Paris) 72:669.
  2. Kalea AZ, et al. 2009. Clin. Sci. (Lond) 116:621.
Gene ID
177 View all products for this Gene ID
UniProt
View information about RAGE on UniProt.org

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