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HRP anti-TFEB Antibody
产品名称:
HRP anti-TFEB Antibody
产品类别:
抗体
产品编号:
852003
产品应用:
852003
[价格]
规格 价格 库存
25µg ¥ 138 1

产品详情

Product Details

Verified Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
Preparation
The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.01 - 0.1 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2734644 (BioLegend Cat. No. 852003) AB_2734645 (BioLegend Cat. No. 852004)

Antigen Details

Structure
TFEB is a 476 amino acid protein with a molecular weight mass of approximately 53kD.
Distribution

Tissue distribution: TFEB is expressed in numerous cell types of the central nervous system (CNS).

Cellular distribution: Cytosolic and nucleus.

Function
TFEB is a major regulator of autophagy and lysosomal biogenesis.
Interaction
TFEB interacts with the mTOR complex and its activity is thought to be regulated through the phosphorylation by mTOR.
Biology Area
Cell Biology, Neurodegeneration, Neuroscience, Neuroscience Cell Markers, Protein Trafficking and Clearance, Transcription Factors
Molecular Family
Nuclear Markers
Antigen References
  1. Martini-Stoica H, et al. 2016. Trends Neurosci. 221-234.
  2. Napolitano G, Ballabio A. 2016. J. Cell Sci. 129: 2475-81.
  3. Raben N, Puertollano R. 2016. Annu. Rev. Cell Dev. Biol. 32: 255-278.
Gene ID
7942 View all products for this Gene ID
UniProt
View information about TFEB on UniProt.org

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