Purified anti-Claudin-1 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 253	1

规格

价格

库存

100µg

￥ 253

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Synthetic Claudin-1 peptide conjugated to KLH (TPRPYPKPAPSSGKDYVC)
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB -?Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: This clone has no cross-reactivity with mouse (in house tested).
RRID: AB_2687205 (BioLegend Cat. No. 697801) AB_2687191 (BioLegend Cat. No. 697802)

Structure: 211 amino acids with a predicted molecular weight of 22.7 kD and observed approximately 18kD. Multi-pass membrane protein with 4 transmembrane domains.
Distribution: Cell membrane. Cell junction.
Function: Claudin-1 is an integral membrane protein that forms tight junctions between skin epithelial cells to form barriers, regulate paracellular transport, and maintain cell polarity.
Interaction: Forms homopolymers and heteropolymers with other claudin family proteins. Interacts with CLDN3, TJP1/ZO-1, TJP2/ZO-2, TJP3/ZO-3, MPDZ, and PATJ.
Cell Type: Mesenchymal Stem Cells
Biology Area: Stem Cells
Antigen References: 1.?Suh Y,?et al.?2017.?Oncogene. 36:1167.
2.?Tokumasu R,?et al.?2016.?Proc. Natl. Acad. Sci.?USA. 113:E4061.
3.?Zhou B,?et al.?2015.?J. Clin. Med.?4:1960.
4.?Saeedi BJ,?et al.?2015.?Mol. Biol. Cell.?26:2252.
5.?Huang J,?et al.?2015.?Oncotarget. 6:1652.
6.?Izraely S,?et al.?2015.?Int. J. Cancer.?136:1296.
Gene ID: 9076 View all products for this Gene ID
UniProt: View information about Claudin-1 on UniProt.org