Ultra-LEAF™ Purified anti-human β-NGF A-上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 270	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Recombinant Human β-NGF

Formulation

0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is <0.01 EU/?g of the protein (<0.001 ng/?g of the protein) as determined by the LAL test.

Preparation

The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.

Concentration

The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.

Application

Neut - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by neutralization of the proliferation induced by recombinant human β-NGF (0.08 ?g/mL) on TF-1 human erythroleukemia cells. ND₅₀ range: 0.1 - 0.8 ?g/mL. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations

Wu BW, et al. 2022. Viruses. 14:. PubMed

RRID

AB_2814462 (BioLegend Cat. No. 617903) AB_2814463 (BioLegend Cat. No. 617904)

Antigen Details

Structure

Dimer

Distribution

Hypothalamus, pituitary, thyroid gland, testes, epididymis, vascular smooth muscle cells, fibroblasts, myofibroblasts, mast cells, eosinophils.

Function

β-NGF is important for maintaining neuron homeostasis.

Interaction

Neurons, astrocytes, eosinophils, B, T, and mast cells.

Ligand/Receptor

Low-affinity NGF receptor (p75NTR); high-affinity NGF receptor (TrkA).

Cell Type

B cells, Eosinophils, Fibroblasts, Mast cells, Mature Neurons, Neural Stem Cells, Neurons, T cells

Biology Area

Cell Biology, Cell Proliferation and Viability, Neurodegeneration, Neuroscience, Synaptic Biology

Molecular Family

Cytokines/Chemokines, Growth Factors

Antigen References

Ullrich A, et al. 1983. Nature. 303:821.
Klein R, et al. 1991. Cell. 65:189.
Welker P, et al. 2000. Immunology 99:418.
Fahnestock M, et al. 2004. Prog. Brain Res. 146:101.
Bruno MA. Cuello AC. 2006. Proc. Natl. Acad. Sci. USA 103:6735.
Aloe L, et al. 2015. Curr. Neuropharmacol. 13:294.

Gene ID

4803 View all products for this Gene ID

UniProt

View information about beta-NGF on UniProt.org

上海细胞库

原代细胞

细胞培养

细胞服务

酶联试剂盒

生化试剂盒

PCR试剂盒

抗体蛋白

试剂耗材

首页 > 抗体蛋白 > 抗体

产品详情

Product Details

Antigen Details

联系我们