Purified anti-DJ-1 (PARK7) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 106	1

规格

价格

库存

25µg

￥ 106

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Recombinant Human DJ-1
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB -?Quality tested
Direct ELISA, IHC-P -?Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 - 5.0 ?g per ml. For Direct ELISA, a concentration range of 0.002 - 1.0 ?g/mL is recommended. For immunohistochemistry, a concentration range of 1.0 - 5.0 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2721732 (BioLegend Cat. No. 851501) AB_2721733 (BioLegend Cat. No. 851502)

Structure: Human DJ-1 is a 189 amino acid protein with an apparent molecular weight of 20 kD. The protein consists of 7 β-strands and 7 α-helices, and exits as a dimer.
Distribution: Tissue distribution: Highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart. Detected at slightly lower levels in brain and placenta.
Cellular distribution: Mitochondria, nucleus, cytosol, plasma membrane, and extracellular.
Function: DJ-1 functions as an oxidative stress sensor and redox-sensitive chaperone.
Interaction: PINK1, Parkin, EFCAB6/DJBP, OTUD7B, BBS1, HIPK1, CLCF1 and MTERF.
Biology Area: Cell Biology, Mitochondrial Function, Neurodegeneration, Neuroinflammation, Neuroscience, Neuroscience Cell Markers, Protein Misfolding and Aggregation, Protein Trafficking and Clearance
Molecular Family: Mitochondrial Markers
Antigen References: 1.?Saito Y. 2014.?J. Clin. Biochem. Nutr.?54(3):138-44.?PubMed
2.?Ariga H,?et al.?2013.?Oxid. Med. Cell Longev.?2013:683920.?PubMed
3.?Bonifati V,?et al.?2003.?Science?(5604): 256–9.?PubMed
Gene ID: 11315 View all products for this Gene ID
UniProt: View information about DJ-1 on UniProt.org