首页 > 抗体蛋白 > 抗体
HRP anti-DJ-1 (PARK7) Antibody
产品名称:
HRP anti-DJ-1 (PARK7) Antibody
产品类别:
抗体
产品编号:
851504
产品应用:
851504
[价格]
规格 价格 库存
100µg ¥ 317 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant Human DJ-1
Formulation
This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
Preparation
The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Application

WB - Quality tested
IHC-P - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.2 - 1.0 ?g per ml. For immunohistochemistry, a concentration range of 1.0 - 5.0 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2734643 (BioLegend Cat. No. 851504)

Antigen Details

Structure
Human DJ-1 is a 189 amino acid protein with an apparent molecular weight of 20 kD. The protein consists of 7 β-strands and 7 α-helices, and exits as a dimer.
Distribution

Tissue distribution: Highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart. Detected at slightly lower levels in brain and placenta.
Cellular distribution: Mitochondria, nucleus, cytosol, plasma membrane, and extracellular.

Function
DJ-1 functions as an oxidative stress sensor and redox-sensitive chaperone.
Interaction
PINK1, Parkin, EFCAB6/DJBP, OTUD7B, BBS1, HIPK1, CLCF1 and MTERF.
Biology Area
Cell Biology, Mitochondrial Function, Neurodegeneration, Neuroinflammation, Neuroscience, Neuroscience Cell Markers, Protein Misfolding and Aggregation, Protein Trafficking and Clearance
Molecular Family
Mitochondrial Markers
Antigen References
  1. Saito Y. 2014. J. Clin. Biochem. Nutr. 54(3):138-44. PubMed
  2. Ariga H, et al. 2013. Oxid. Med. Cell Longev. 2013:683920. PubMed
  3. Bonifati V, et al. 2003. Science (5604): 256–9. PubMed
Gene ID
11315 View all products for this Gene ID
UniProt
View information about DJ-1 on UniProt.org

联系我们

TEL:021-34661275  点击拨打热线