Ultra-LEAF™ Purified anti-human CD95 (FAS) A-上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 270	1

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Recombinant human FAS
Formulation: 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is <0.01 EU/?g of the protein (<0.001 ng/?g of the protein) as determined by the LAL test.
Preparation: The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Concentration: The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
Application: Blocking -?Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by blocking activity. The ND₅₀?is 0.01– 0.05 ?g/mL. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2716048 (BioLegend Cat. No. 684401) AB_2716055 (BioLegend Cat. No. 684402)

Structure: Trimer
Distribution: Activated human T cells, ?B cells, malignant human lymphoid cell lines, fibroblasts, dendritic cells, thymocytes, macrophages, cardiomyocytes, hepatocytes, FAS is expressed on most cell types.
Function: Apoptotic clearance of virus-infected cells, contributes to shutdown of chronic immune responses and to maintenance of peripheral tolerance. Soluble FAS modulates cell apoptosis.
Interaction: Lymphocytes T (mainly CD8+), NK cells.
Ligand/Receptor: FASL (TNFSF6)
Cell Type: T cells, B cells, Fibroblasts, Dendritic cells, Thymocytes, Macrophages
Biology Area: Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Immunology
Molecular Family: CD Molecules
Antigen References: 1. Oehm A,?et al.?1992.?J Biol Chem.?267:10709.
2. Cheng J,?et al.?1994.?Science.?263:1759.?
3. Papoff G,?et al.?1996.?J Immunol.?156:4622.?
4. Rescigno M,?et al.?2000.?J Exp Med.?192:1661.?
5. Giroux M,?et al.?2005.?Blood.?105:703.?
6. Kovacic N,?et al.?2010.?Expert Opin Ther Targets?14:1121.
Gene ID: 355 View all products for this Gene ID
UniProt: View information about CD95 on UniProt.org